Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABCB1 | P08183 | 1/20 | 0.52 |
| ▸ | RIPK1 | Q13546 | 5/20 | 0.50 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.49 |
| ▸ | RORC | P51449 | 1/20 | 0.46 |
| ▸ | BCHE | P06276 | 1/20 | 0.45 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.45 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.45 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.45 |
| ▸ | NR1H2 | P55055 | 2/20 | 0.45 |
| ▸ | NR1H3 | Q13133 | 2/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4870228 | 1.00 | ABCB1 (0.52) | ABCB1RIPK1GPR119RORCBCHE | |
| SCHEMBL6182669 | 0.91 | ABCB1 (0.48) | ABCB1RIPK1GPR119RORCCHRM2 | |
| SCHEMBL15730324 | 0.91 | ABCB1 (0.48) | ABCB1RIPK1GPR119RORCCHRM2 | |
| SCHEMBL18639491 | 0.91 | ABCB1 (0.48) | ABCB1RIPK1GPR119RORCCHRM2 | |
| SCHEMBL15730078 | 0.91 | ABCB1 (0.48) | ABCB1RIPK1GPR119RORCCHRM2 | |
| SCHEMBL15730571 | 0.91 | ABCB1 (0.48) | ABCB1RIPK1GPR119RORCCHRM2 | |
| SCHEMBL859599 | 0.90 | FFAR2 (0.51) | ABCB1RIPK1GPR119 | |
| SCHEMBL2896922 | 0.90 | FFAR2 (0.51) | ABCB1RIPK1GPR119 | |
| SCHEMBL475745 | 0.90 | FFAR2 (0.51) | ABCB1RIPK1GPR119 | |
| SCHEMBL6183606 | 0.90 | FFAR2 (0.51) | ABCB1RIPK1GPR119 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7423059-B2 | Pharmaceutically active compounds and methods of use | WYETH (US) | 2008-09-09 | — | — | US | disclosed |