Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR2 | O15552 | 3/20 | 0.51 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.47 |
| ▸ | RIPK1 | Q13546 | 2/20 | 0.45 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5156869 | 1.00 | FFAR2 (0.51) | FFAR2ABCB1RIPK1GPR119 | |
| SCHEMBL475744 | 1.00 | FFAR2 (0.51) | FFAR2ABCB1RIPK1GPR119 | |
| SCHEMBL30720983 | 1.00 | FFAR2 (0.51) | FFAR2ABCB1RIPK1GPR119 | |
| SCHEMBL29040317 | 1.00 | FFAR2 (0.51) | FFAR2ABCB1RIPK1GPR119 | |
| SCHEMBL2896922 | 1.00 | FFAR2 (0.51) | FFAR2ABCB1RIPK1GPR119 | |
| SCHEMBL475745 | 1.00 | FFAR2 (0.51) | FFAR2ABCB1RIPK1GPR119 | |
| SCHEMBL859599 | 1.00 | FFAR2 (0.51) | FFAR2ABCB1RIPK1GPR119 | |
| SCHEMBL28511990 | 0.90 | ABCB1 (0.49) | FFAR2ABCB1RIPK1GPR119 | |
| SCHEMBL4870228 | 0.90 | ABCB1 (0.52) | ABCB1RIPK1GPR119 | |
| SCHEMBL14074143 | 0.90 | ABCB1 (0.52) | ABCB1RIPK1GPR119 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11873298-B2 | Compounds and uses thereof | JANSSEN PHARMACEUTICA NV (BE) | 2024-01-16 | — | — | US | disclosed |
| US-20200262828-A1 | COMPOUNDS AND USES THEREOF | JANSSEN PHARMACEUTICA NV (BE) | 2020-08-20 | — | — | US | disclosed |
| US-20050256166-A1 | Nitrogen-containing compounds | ONO PHARMACEUTICAL CO., LTD. (JP) | 2005-11-17 | — | — | US | disclosed |
| EP-1535906-A1 | NITROGEN-CONTAINING COMPOUNDS | ONO PHARMACEUTICAL CO., LTD. (JP) | 2005-06-01 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050256166-A1 | Nitrogen-containing compounds | DPP4, DPP3, DPP8 | FFAR2 3194/4885ABCB1 2250/4885RIPK1 2128/4885 |
| US-11873298-B2 | Compounds and uses thereof | NLN, ACHE, CLN6 | FFAR2 4001/4885ABCB1 129/4885RIPK1 4414/4885 |
| US-20200262828-A1 | COMPOUNDS AND USES THEREOF | NLN, ACHE, CLN6 | FFAR2 4001/4885ABCB1 129/4885RIPK1 4414/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.