SCHEMBL1407428

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL1407475	0.93	NR1H2 (0.46)	NR1H2NR1H3SMN1; SMN2KDM4EALDH1A1
	SCHEMBL1407455	0.93	NR1H2 (0.45)	NR1H2NR1H3KMT2AMEN1KDM4E
	SCHEMBL1407321	0.91	NR1H2 (0.47)	NR1H2NR1H3KMT2ASMN1; SMN2MEN1
	SCHEMBL1407316	0.91	P2RX7 (0.40)	NR1H2NR1H3KMT2AMEN1KDM4E
	SCHEMBL1407448	0.90	NR1H2 (0.47)	NR1H2NR1H3KMT2ASMN1; SMN2MEN1
	SCHEMBL1408297	0.88	NR1H2 (0.43)	NR1H2NR1H3KMT2ASMN1; SMN2MEN1
	SCHEMBL1407447	0.86	NR1H2 (0.47)	NR1H2NR1H3KMT2ASMN1; SMN2MEN1
	SCHEMBL1407384	0.86	KMT2A (0.48)	NR1H2NR1H3KMT2AMEN1KDM4E
	SCHEMBL1407762	0.85	NR1H2 (0.48)	NR1H2NR1H3NR1I2NR3C1KDM4E
	SCHEMBL4030775	0.83	CYP1A1 (0.39)	KMT2ASMN1; SMN2MEN1KDM4EALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.