SCHEMBL1407455

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL1407428	0.93	NR1H2 (0.47)	NR1H2NR1H3ALDH1A1GAAKDM4E
	SCHEMBL1407475	0.92	NR1H2 (0.46)	NR1H2NR1H3ALDH1A1GAAKDM4E
	SCHEMBL1407316	0.90	P2RX7 (0.40)	NR1H2NR1H3L3MBTL1ALDH1A1GAA
	SCHEMBL1407200	0.89	NR1H2 (0.45)	NR1H2NR1H3NTRK1ALDH1A1GAA
	SCHEMBL1407447	0.89	NR1H2 (0.47)	NR1H2NR1H3ALDH1A1HSP90AA1KDM4E
	SCHEMBL1407812	0.88	NR1H2 (0.43)	NR1H2NR1H3NTRK1ATML3MBTL1
	SCHEMBL1407762	0.88	NR1H2 (0.48)	NR1H2NR1H3ALDH1A1GAAKDM4E
	SCHEMBL1407384	0.87	KMT2A (0.48)	NR1H2NR1H3L3MBTL1ALDH1A1GAA
	SCHEMBL1408297	0.85	NR1H2 (0.43)	NR1H2NR1H3KDM4EMEN1POLB
	SCHEMBL4030775	0.84	CYP1A1 (0.39)	ALDH1A1HSP90AA1KDM4EMEN1POLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.