Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS1 | P23219 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 7/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 6/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.47 |
| ▸ | MAPT | P10636 | 6/20 | 0.47 |
| ▸ | HPGD | P15428 | 4/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.47 |
| ▸ | LMNA | P02545 | 3/20 | 0.47 |
| ▸ | MEN1 | O00255 | 2/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.47 |
| ▸ | SLC15A2 | Q16348 | 2/20 | 0.47 |
| ▸ | CTDSP1 | Q9GZU7 | 2/20 | 0.47 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.47 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.47 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.45 |
| ▸ | BLM | P54132 | 1/20 | 0.45 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18623606 | 1.00 | PTGS1 (0.48) | PTGS1ALDH1A1TDP1HSD17B10KDM4E | |
| SCHEMBL16181512 | 0.91 | PTGS1 (0.49) | PTGS1ALDH1A1TDP1HSD17B10KDM4E | |
| SCHEMBL4346431 | 0.89 | PTGS1 (0.54) | PTGS1ALDH1A1TDP1HSD17B10KDM4E | |
| SCHEMBL9013344 | 0.89 | PTGS1 (0.48) | PTGS1ALDH1A1TDP1HSD17B10KDM4E | |
| SCHEMBL9013350 | 0.89 | PTGS1 (0.48) | PTGS1ALDH1A1TDP1HSD17B10KDM4E | |
| SCHEMBL4341952 | 0.89 | PTGS1 (0.54) | PTGS1ALDH1A1TDP1HSD17B10KDM4E | |
| SCHEMBL9371427 | 0.89 | PTGS1 (0.49) | PTGS1ALDH1A1TDP1HSD17B10KDM4E | |
| SCHEMBL9371430 | 0.89 | PTGS1 (0.49) | PTGS1ALDH1A1TDP1HSD17B10KDM4E | |
| SCHEMBL9699333 | 0.88 | TDP1 (0.58) | PTGS1ALDH1A1TDP1HSD17B10KDM4E | |
| SCHEMBL9699338 | 0.88 | TDP1 (0.58) | PTGS1ALDH1A1TDP1HSD17B10KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7427680-B2 | Fluorogenic substrates for BETA-lactamase gene expression | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2008-09-23 | — | — | US | disclosed |