Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS1 | P23219 | 1/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 5/20 | 0.46 |
| ▸ | MAPT | P10636 | 4/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.46 |
| ▸ | HPGD | P15428 | 3/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | SLC15A2 | Q16348 | 2/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.46 |
| ▸ | CTDSP1 | Q9GZU7 | 2/20 | 0.46 |
| ▸ | NR1I2 | O75469 | 2/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.46 |
| ▸ | BLM | P54132 | 1/20 | 0.46 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.46 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18623606 | 0.91 | PTGS1 (0.48) | PTGS1L3MBTL1ALDH1A1HSD17B10MAPT | |
| SCHEMBL14074295 | 0.91 | PTGS1 (0.48) | PTGS1L3MBTL1ALDH1A1HSD17B10MAPT | |
| SCHEMBL14065427 | 0.87 | TDP1 (0.61) | PTGS1L3MBTL1ALDH1A1HSD17B10MAPT | |
| SCHEMBL9477097 | 0.85 | CTDSP1 (0.55) | PTGS1L3MBTL1ALDH1A1HSD17B10MAPT | |
| SCHEMBL9477095 | 0.85 | CTDSP1 (0.55) | PTGS1L3MBTL1ALDH1A1HSD17B10MAPT | |
| SCHEMBL11673058 | 0.84 | CA5A (0.56) | PTGS1L3MBTL1ALDH1A1HSD17B10MAPT | |
| SCHEMBL11710209 | 0.83 | PTGS1 (0.55) | PTGS1L3MBTL1ALDH1A1HSD17B10MAPT | |
| SCHEMBL11710215 | 0.83 | PTGS1 (0.55) | PTGS1L3MBTL1ALDH1A1HSD17B10MAPT | |
| SCHEMBL11674593 | 0.83 | TDP1 (0.62) | PTGS1L3MBTL1ALDH1A1HSD17B10MAPT | |
| SCHEMBL14065430 | 0.83 | TDP1 (0.62) | PTGS1L3MBTL1ALDH1A1HSD17B10MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8865891-B2 | Optically-detectable enzyme substrates and their method of use | Life Technologies Corporation (US) | 2014-10-21 | — | — | US | disclosed |