SCHEMBL9699333

SCHEMBL9699333

O=C(Cc1ccccc1)N[C@@H]1C(=O)N2C(C(=O)OC(c3ccccc3)c3ccccc3)=C(CCl)CS[C@H]12

nearest known ligand 0.58

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ TDP1 Q9NUW8 5/20 0.58
▸ CTDSP1 Q9GZU7 2/20 0.58
▸ MAPK1 P28482 1/20 0.57
▸ ALDH1A1 P00352 6/20 0.56
▸ L3MBTL1 Q9Y468 2/20 0.56
▸ MAPT P10636 4/20 0.55
▸ POLB P06746 1/20 0.55
▸ PKM P14618 1/20 0.55
▸ HTT P42858 1/20 0.55
▸ DUSP3 P51452 1/20 0.55
▸ PTPN5 P54829 1/20 0.55
▸ PTPN11 Q06124 1/20 0.55
▸ PLCG1 P19174 1/20 0.52
▸ PTGS1 P23219 1/20 0.49
▸ KDM4E B2RXH2 4/20 0.48
▸ HSD17B10 Q99714 4/20 0.48
▸ KMT2A Q03164 3/20 0.48
▸ CYP3A4 P08684 3/20 0.48
▸ MEN1 O00255 2/20 0.48
▸ HPGD P15428 2/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6513287 1.00 TDP1 (0.58) TDP1CTDSP1MAPK1ALDH1A1L3MBTL1
SCHEMBL27277447 1.00 TDP1 (0.58) TDP1CTDSP1MAPK1ALDH1A1L3MBTL1
SCHEMBL7522418 1.00 TDP1 (0.58) TDP1CTDSP1MAPK1ALDH1A1L3MBTL1
SCHEMBL9699338 1.00 TDP1 (0.58) TDP1CTDSP1MAPK1ALDH1A1L3MBTL1
SCHEMBL9099342 1.00 TDP1 (0.58) TDP1CTDSP1MAPK1ALDH1A1L3MBTL1
SCHEMBL1132359 0.92 TDP1 (0.59) TDP1CTDSP1MAPK1ALDH1A1L3MBTL1
SCHEMBL11015972 0.92 TDP1 (0.59) TDP1CTDSP1MAPK1ALDH1A1L3MBTL1
SCHEMBL7804219 0.92 TDP1 (0.59) TDP1CTDSP1MAPK1ALDH1A1L3MBTL1
SCHEMBL10579475 0.92 TDP1 (0.59) TDP1CTDSP1MAPK1ALDH1A1L3MBTL1
SCHEMBL9642504 0.92 TDP1 (0.59) TDP1CTDSP1MAPK1ALDH1A1L3MBTL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4498128-A2 SATELLITE NAVIGATION RECEIVING SYSTEM Fuba Automotive Electronics GmbH (DE) 2025-01-29 — — EP disclosed
US-20240240226-A1 FLUOROGENIC ASSAY FOR RAPID SCREENING OF BACTERIAL BETA-LACTAMASE ACTIVITY UNIV LELAND STANFORD JUNIOR (US) 2024-07-18 — — US disclosed
CN-113214292-B Industrial production method for preparing penicillin sulfoxide by continuously oxidizing penicillin 华北制药股份有限公司 2023-02-28 — — CN disclosed
CN-114805393-A Preparation method of cefprozil 南京亿华药业有限公司 2022-07-29 — — CN disclosed
US-9677112-B2 β-lactamase substrates and methods of their use for the diagnosis of tuberculosis THE TEXAS A&M UNIVERSITY SYSTEM (US) 2017-06-13 — — US disclosed
US-20150167048-A1 BETA-LACTAMASE SUBSTRATES AND METHODS OF THEIR USE FOR THE DIAGNOSIS OF TUBERCULOSIS THE TEXAS A&M UNIVERSITY SYSTEM (US) 2015-06-18 — — US disclosed
US-7427680-B2 Fluorogenic substrates for BETA-lactamase gene expression THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2008-09-23 — — US disclosed
US-7427680-B2 Fluorogenic substrates for BETA-lactamase gene expression THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2008-09-23 — — US disclosed
US-5158946-A Antibiotics, bactericides BEECHAM GROUP P.L.C. (GB) 1992-10-27 — — US disclosed
US-5064649-A CEPHALOSPORIN DERIVATIVES BEECHAM GROUP P.L.C. (GB) 1991-11-12 — — US disclosed
EP-0418020-A2 Cephalosporinderivatives, process for their preparation and pharmaceutical compositions BEECHAM GROUP PLC (GB) 1991-03-20 — — EP disclosed
EP-0359536-A2 Cephalosporin compounds, process for their preparation and pharmaceutical compositions BEECHAM GROUP PLC (GB) 1990-03-21 — — EP disclosed
US-4880795-A Cephalosporins BAYER AKTIENGESELLSCHAFT (DE) 1989-11-14 — — US disclosed
US-4686216-A 7-[2-(2-aminothiazol-4-yl)-2-oximino-acetamido-3-quaternary-ammonium-methyl-3-cephem-4-carboxylates BAYER AKTIENGESELLSCHAFT (DE) 1987-08-11 — — US disclosed
US-4632918-A Novel β-lactam antibiotics BAYER AKTIENGESELLSCHAFT (DE) 1986-12-30 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20150167048-A1 BETA-LACTAMASE SUBSTRATES AND METHODS OF THEIR USE FOR THE DIAGNOSIS OF TUBERCULOSIS PGLS, ENGASE, BPHL TDP1 2256/4885CTDSP1 1636/4885MAPK1 4733/4885
US-20240240226-A1 FLUOROGENIC ASSAY FOR RAPID SCREENING OF BACTERIAL BETA-LACTAMASE ACTIVITY CDA, CMBL, CTSF TDP1 3244/4885CTDSP1 2743/4885MAPK1 4714/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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