Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 5/20 | 0.69 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.69 |
| ▸ | PKM | P14618 | 1/20 | 0.69 |
| ▸ | NPC1 | O15118 | 2/20 | 0.57 |
| ▸ | RAB9A | P51151 | 2/20 | 0.57 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.57 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.57 |
| ▸ | PIM1 | P11309 | 1/20 | 0.57 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.57 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.57 |
| ▸ | TP53 | P04637 | 1/20 | 0.57 |
| ▸ | HTT | P42858 | 1/20 | 0.57 |
| ▸ | SUCNR1 | Q9BXA5 | 1/20 | 0.55 |
| ▸ | DHODH | Q02127 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2624522 | 0.89 | KMT2A (0.64) | MEN1KMT2APKMNPC1RAB9A | |
| SCHEMBL2274678 | 0.87 | PYGM (0.57) | MEN1KMT2APKMNPC1RAB9A | |
| SCHEMBL2270661 | 0.87 | ACLY (0.58) | MEN1KMT2APKMNPC1RAB9A | |
| SCHEMBL14075227 | 0.86 | MEN1 (0.78) | MEN1KMT2APKMNPC1RAB9A | |
| SCHEMBL6353666 | 0.85 | AKR1C2 (0.73) | MEN1KMT2APKMNPC1RAB9A | |
| SCHEMBL6359536 | 0.85 | KMT2A (0.78) | MEN1KMT2APKMNPC1RAB9A | |
| SCHEMBL14075247 | 0.84 | MEN1 (0.64) | MEN1KMT2APKMCHEK1PIM1 | |
| SCHEMBL14075228 | 0.83 | AKR1C2 (0.74) | MEN1KMT2APKMNPC1RAB9A | |
| SCHEMBL2029098 | 0.83 | MEN1 (1.00) | MEN1KMT2APKMNPC1RAB9A | |
| SCHEMBL10561464 | 0.82 | MEN1 (0.69) | MEN1KMT2APKMRAB9ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7429677-B2 | Small molecule entry inhibitors | TIBOTEC PHARMACEUTICALS LTD. (IE) | 2008-09-30 | — | — | US | disclosed |
| US-7429677-B2 | Small molecule entry inhibitors | TIBOTEC PHARMACEUTICALS LTD. (IE) | 2008-09-30 | — | — | US | disclosed |