Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | QPCT | Q16769 | 19/20 | 0.46 |
| ▸ | QPCTL | Q9NXS2 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5053561 | 1.00 | QPCT (0.46) | QPCTQPCTLNPC1MAPTRAB9A | |
| SCHEMBL16472530 | 0.90 | QPCT (0.45) | QPCTQPCTL | |
| SCHEMBL5056594 | 0.87 | QPCT (0.39) | QPCTQPCTLNPC1MAPTRAB9A | |
| SCHEMBL5056589 | 0.87 | QPCT (0.39) | QPCTQPCTLNPC1MAPTRAB9A | |
| SCHEMBL14217706 | 0.84 | QPCT (0.42) | QPCTQPCTL | |
| SCHEMBL5062202 | 0.84 | QPCT (0.45) | QPCTQPCTL | |
| SCHEMBL14217788 | 0.84 | QPCT (0.45) | QPCTQPCTL | |
| SCHEMBL14076657 | 0.80 | QPCT (0.46) | QPCTQPCTL | |
| SCHEMBL5053692 | 0.80 | QPCT (0.46) | QPCTQPCTL | |
| SCHEMBL5056691 | 0.79 | QPCT (0.50) | QPCTQPCTL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080221086-A1 | Novel Inhibitors of Glutaminyl Cyclase | PROBIODRUG AG (DE) | 2008-09-11 | — | — | US | disclosed |
| US-20080221086-A1 | Novel Inhibitors of Glutaminyl Cyclase | PROBIODRUG AG (DE) | 2008-09-11 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080221086-A1 | Novel Inhibitors of Glutaminyl Cyclase | GLS, GLS2, GLUL | QPCT 9/4885QPCTL 57/4885NPC1 2022/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.