Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BTK | Q06187 | 6/20 | 0.60 |
| ▸ | JAK3 | P52333 | 4/20 | 0.60 |
| ▸ | ATM | Q13315 | 2/20 | 0.55 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.55 |
| ▸ | JAK2 | O60674 | 1/20 | 0.55 |
| ▸ | STK16 | O75716 | 1/20 | 0.55 |
| ▸ | FYN | P06241 | 1/20 | 0.55 |
| ▸ | SRC | P12931 | 1/20 | 0.55 |
| ▸ | FLT1 | P17948 | 1/20 | 0.55 |
| ▸ | KDR | P35968 | 1/20 | 0.55 |
| ▸ | HPGD | P15428 | 3/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.52 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.52 |
| ▸ | HTT | P42858 | 1/20 | 0.52 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.52 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.52 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.52 |
| ▸ | TGM2 | P21980 | 1/20 | 0.48 |
| ▸ | EGFR | P00533 | 7/20 | 0.48 |
| ▸ | ITK | Q08881 | 4/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14078365 | 0.82 | ATM (0.59) | BTKJAK3ATMJAK2STK16 | |
| SCHEMBL1679420 | 0.82 | JAK3 (0.54) | BTKJAK3FGFR1JAK2STK16 | |
| SCHEMBL12807638 | 0.82 | BTK (0.79) | BTKJAK3JAK2STK16FYN | |
| SCHEMBL12736101 | 0.81 | BTK (0.60) | BTKJAK3FGFR1JAK2STK16 | |
| SCHEMBL9919165 | 0.78 | JAK3 (0.56) | BTKJAK3FGFR1JAK2STK16 | |
| SCHEMBL7986579 | 0.76 | RAB9A (0.71) | BTKJAK3FGFR1STK16FYN | |
| SCHEMBL31069810 | 0.76 | TGM2 (0.66) | ALDH1A1MAPK1TGM2EGFRITK | |
| SCHEMBL1383792 | 0.76 | TGM2 (0.66) | ALDH1A1MAPK1TGM2EGFRITK | |
| SCHEMBL1679374 | 0.75 | JAK3 (0.58) | BTKJAK3ATMFGFR1JAK2 | |
| SCHEMBL4590789 | 0.75 | JAK3 (0.61) | BTKJAK3JAK2STK16FYN |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080207613-A1 | Selective Kinase Inhibitors | CYTOPIA RESEARCH PTY LTD (AU) | 2008-08-28 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080207613-A1 | Selective Kinase Inhibitors | LCK, CHUK, CSK | BTK 7/4885JAK3 47/4885ATM 200/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.