Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | PSEN1 | P49768 | 1/20 | 0.37 |
| ▸ | PSEN2 | P49810 | 1/20 | 0.37 |
| ▸ | APH1B | Q8WW43 | 1/20 | 0.37 |
| ▸ | NCSTN | Q92542 | 1/20 | 0.37 |
| ▸ | APH1A | Q96BI3 | 1/20 | 0.37 |
| ▸ | PSENEN | Q9NZ42 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.35 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.35 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14079238 | 0.90 | RAB9A (0.39) | SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL5108351 | 0.83 | PTGS2 (0.38) | ALDH1A1SLC6A3 | |
| SCHEMBL14097229 | 0.80 | DPP4 (0.33) | SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL14079295 | 0.78 | DPP4 (0.32) | MAPTSLC6A2SLC6A4SLC6A3 | |
| SCHEMBL5101639 | 0.75 | NPC1 (0.36) | ALDH1A1MAPT | |
| SCHEMBL13483112 | 0.74 | TACR1 (0.35) | — | |
| SCHEMBL6012706 | 0.72 | — | — | |
| SCHEMBL13482857 | 0.71 | HTR2A (0.38) | — | |
| SCHEMBL5094877 | 0.69 | PSEN1 (0.36) | ALDH1A1PSEN1PSEN2APH1BNCSTN | |
| SCHEMBL5094876 | 0.68 | SLC6A2 (0.36) | PSEN1PSEN2APH1BNCSTNAPH1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7420059-B2 | HMG-CoA reductase inhibitors and method | BRISTOL-MYERS SQUIBB COMPANY (US) | 2008-09-02 | — | — | US | disclosed |
| US-7420059-B2 | HMG-CoA reductase inhibitors and method | BRISTOL-MYERS SQUIBB COMPANY (US) | 2008-09-02 | — | — | US | disclosed |