Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CDK4 | P11802 | 3/20 | 0.45 |
| ▸ | CCND1 | P24385 | 3/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | PDE5A | O76074 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 4/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | HPGD | P15428 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | THRB | P10828 | 1/20 | 0.41 |
| ▸ | HDAC3 | O15379 | 5/20 | 0.41 |
| ▸ | HDAC1 | Q13547 | 5/20 | 0.41 |
| ▸ | HDAC2 | Q92769 | 5/20 | 0.41 |
| ▸ | NCOR2 | Q9Y618 | 3/20 | 0.40 |
| ▸ | TACR1 | P25103 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14078737 | 0.95 | CDK4 (0.45) | CDK4CCND1SMN1; SMN2CYP1A2CYP3A4 | |
| SCHEMBL4737839 | 0.91 | ALOX5 (0.44) | CDK4CCND1SMN1; SMN2CYP1A2CYP3A4 | |
| SCHEMBL14078362 | 0.90 | CDK4 (0.50) | CDK4CCND1SMN1; SMN2MEN1KMT2A | |
| SCHEMBL14078774 | 0.89 | CDK4 (0.49) | CDK4CCND1SMN1; SMN2MEN1KMT2A | |
| SCHEMBL4738871 | 0.88 | CYP2D6 (0.42) | CDK4CCND1SMN1; SMN2CYP1A2CYP3A4 | |
| SCHEMBL14078758 | 0.86 | CDK4 (0.47) | CDK4CCND1MEN1KMT2AHDAC3 | |
| SCHEMBL14078438 | 0.86 | CDK4 (0.49) | CDK4CCND1SMN1; SMN2MEN1KMT2A | |
| SCHEMBL14079246 | 0.85 | CDK4 (0.46) | CDK4CCND1SMN1; SMN2MEN1KMT2A | |
| SCHEMBL14079284 | 0.85 | CDK4 (0.47) | CDK4CCND1MEN1KMT2AHDAC3 | |
| SCHEMBL14078441 | 0.85 | CDK4 (0.48) | CDK4CCND1MEN1KMT2AHDAC3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080221195-A1 | 1,2-DIARYLACETYLENE DERIVATIVES OF ACYLTRYPTOPHANOLS | BAYER SCHERING PHARMA AG (DE) | 2008-09-11 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080221195-A1 | 1,2-DIARYLACETYLENE DERIVATIVES OF ACYLTRYPTOPHANOLS | FSHR, GNRHR, TPH1 | CDK4 3792/4885CCND1 443/4885SMN1; SMN2 3600/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.