Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SERPINE1 | P05121 | 2/20 | 0.50 |
| ▸ | BRD4 | O60885 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.45 |
| ▸ | MEN1 | O00255 | 2/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.45 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.45 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.45 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.45 |
| ▸ | IKBKB | O14920 | 1/20 | 0.43 |
| ▸ | PTPN5 | P54829 | 1/20 | 0.43 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.42 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.42 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.41 |
| ▸ | HDAC11 | Q96DB2 | 2/20 | 0.41 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.41 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.41 |
| ▸ | UQCRB | P14927 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14079335 | 0.86 | SERPINE1 (0.54) | SERPINE1BRD4ALDH1A1MEN1KMT2A | |
| SCHEMBL4087564 | 0.86 | SERPINE1 (0.51) | SERPINE1BRD4ALDH1A1MEN1KMT2A | |
| SCHEMBL3984770 | 0.86 | SERPINE1 (0.58) | SERPINE1BRD4ALDH1A1MEN1KMT2A | |
| SCHEMBL3982591 | 0.85 | SERPINE1 (0.50) | SERPINE1BRD4ALDH1A1MEN1KMT2A | |
| SCHEMBL3982480 | 0.84 | SERPINE1 (0.51) | SERPINE1BRD4ALDH1A1MEN1KMT2A | |
| SCHEMBL3953037 | 0.83 | BRD4 (0.52) | SERPINE1BRD4ALDH1A1MEN1KMT2A | |
| SCHEMBL3980708 | 0.83 | SERPINE1 (0.52) | SERPINE1BRD4ALDH1A1MEN1KMT2A | |
| SCHEMBL3979859 | 0.82 | ALDH1A1 (0.51) | SERPINE1BRD4ALDH1A1MEN1KMT2A | |
| SCHEMBL3982665 | 0.82 | SERPINE1 (0.47) | SERPINE1BRD4ALDH1A1MEN1KMT2A | |
| SCHEMBL3980009 | 0.82 | HIF1A (0.56) | SERPINE1BRD4ALDH1A1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7417066-B2 | Inhibitors of soluble adenylate cyclase | SCHERING AG (DE) | 2008-08-26 | — | — | US | disclosed |
| US-7417066-B2 | Inhibitors of soluble adenylate cyclase | SCHERING AG (DE) | 2008-08-26 | — | — | US | disclosed |