Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.51 |
| ▸ | MEN1 | O00255 | 4/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.51 |
| ▸ | POLB | P06746 | 3/20 | 0.51 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.51 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.51 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.51 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.51 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.51 |
| ▸ | SERPINE1 | P05121 | 1/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.49 |
| ▸ | USP2 | O75604 | 1/20 | 0.49 |
| ▸ | PKM | P14618 | 1/20 | 0.49 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.48 |
| ▸ | NAMPT | P43490 | 1/20 | 0.48 |
| ▸ | BRD4 | O60885 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 3/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3985810 | 0.86 | SERPINE1 (0.49) | ALDH1A1MEN1KMT2APOLBNPSR1 | |
| SCHEMBL3984770 | 0.86 | SERPINE1 (0.58) | ALDH1A1MEN1KMT2APOLBNPSR1 | |
| SCHEMBL3980708 | 0.84 | SERPINE1 (0.52) | ALDH1A1MEN1KMT2APOLBNPSR1 | |
| SCHEMBL4087564 | 0.83 | SERPINE1 (0.51) | ALDH1A1MEN1KMT2APOLBNPSR1 | |
| SCHEMBL3982480 | 0.83 | SERPINE1 (0.51) | ALDH1A1MEN1KMT2APOLBNPSR1 | |
| SCHEMBL3947425 | 0.83 | BRD4 (0.53) | ALDH1A1MEN1KMT2APOLBNPSR1 | |
| SCHEMBL14079336 | 0.82 | SERPINE1 (0.50) | ALDH1A1MEN1KMT2APOLBNPSR1 | |
| SCHEMBL3983520 | 0.82 | SERPINE1 (0.48) | ALDH1A1MEN1KMT2APOLBNPSR1 | |
| SCHEMBL14079335 | 0.82 | SERPINE1 (0.54) | ALDH1A1MEN1KMT2APOLBNPSR1 | |
| SCHEMBL3982591 | 0.82 | SERPINE1 (0.50) | ALDH1A1MEN1KMT2APOLBNPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1888058-B1 | INHIBITORS OF SOLUBLE ADENYLATE CYCLASE | BAYER SCHERING PHARMA AG (DE) | 2009-05-20 | — | — | EP | claimed |
| US-7417066-B2 | Inhibitors of soluble adenylate cyclase | SCHERING AG (DE) | 2008-08-26 | — | — | US | claimed |
| EP-1888058-A2 | INHIBITORS OF SOLUBLE ADENYLATE CYCLASE | Bayer Schering Pharma Aktiengesellschaft (DE) | 2008-02-20 | — | — | EP | claimed |
| WO-2006131398-A2 | INHIBITORS OF SOLUBLE ADENYLATE CYCLASE | BAYER SCHERING PHARMA AKTIENGESELLSCHAFT (DE) | 2006-12-14 | — | — | WO | claimed |
| US-20060281744-A1 | Inhibitors of soluble adenylate cyclase | BAYER SCHERING PHARMA AKTIENGESELLSCHAFT (DE) | 2006-12-14 | — | — | US | claimed |
| EP-1888058-B1 | INHIBITORS OF SOLUBLE ADENYLATE CYCLASE | BAYER SCHERING PHARMA AG (DE) | 2009-05-20 | — | — | EP | disclosed |
| US-7417066-B2 | Inhibitors of soluble adenylate cyclase | SCHERING AG (DE) | 2008-08-26 | — | — | US | disclosed |
| US-7417066-B2 | Inhibitors of soluble adenylate cyclase | SCHERING AG (DE) | 2008-08-26 | — | — | US | disclosed |
| US-7417066-B2 | Inhibitors of soluble adenylate cyclase | SCHERING AG (DE) | 2008-08-26 | — | — | US | disclosed |
| EP-1888058-A2 | INHIBITORS OF SOLUBLE ADENYLATE CYCLASE | Bayer Schering Pharma Aktiengesellschaft (DE) | 2008-02-20 | — | — | EP | disclosed |
| WO-2006131398-A2 | INHIBITORS OF SOLUBLE ADENYLATE CYCLASE | BAYER SCHERING PHARMA AKTIENGESELLSCHAFT (DE) | 2006-12-14 | — | — | WO | disclosed |
| US-20060281744-A1 | Inhibitors of soluble adenylate cyclase | BAYER SCHERING PHARMA AKTIENGESELLSCHAFT (DE) | 2006-12-14 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060281744-A1 | Inhibitors of soluble adenylate cyclase | ADCY1, ADCY2, ADCY5 | ALDH1A1 262/4885MEN1 927/4885KMT2A 4556/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.