Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 3/20 | 0.61 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.61 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.61 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.61 |
| ▸ | POLB | P06746 | 1/20 | 0.61 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.61 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.61 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.61 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.61 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.57 |
| ▸ | SERPINE1 | P05121 | 1/20 | 0.53 |
| ▸ | MMP2 | P08253 | 1/20 | 0.48 |
| ▸ | MMP13 | P45452 | 1/20 | 0.48 |
| ▸ | PTPN5 | P54829 | 1/20 | 0.47 |
| ▸ | TP53 | P04637 | 3/20 | 0.47 |
| ▸ | MAPT | P10636 | 3/20 | 0.47 |
| ▸ | THRB | P10828 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.46 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14079338 | 0.87 | ALDH1A1 (0.55) | MEN1KMT2AALDH1A1CYP1A2POLB | |
| SCHEMBL27703445 | 0.87 | ALDH1A1 (0.55) | MEN1KMT2AALDH1A1CYP1A2POLB | |
| SCHEMBL14079337 | 0.87 | ALDH1A1 (0.55) | MEN1KMT2AALDH1A1CYP1A2POLB | |
| SCHEMBL3981321 | 0.85 | ALDH1A1 (0.53) | MEN1KMT2AALDH1A1CYP1A2POLB | |
| SCHEMBL3982872 | 0.82 | ALDH1A1 (0.52) | MEN1KMT2AALDH1A1CYP1A2POLB | |
| SCHEMBL3951941 | 0.75 | BRD4 (0.56) | MEN1KMT2AALDH1A1CYP1A2POLB | |
| SCHEMBL3982487 | 0.74 | ALDH1A1 (0.49) | MEN1KMT2AALDH1A1CYP1A2POLB | |
| Dimethylamine SCHEMBL4931369 | 0.74 | BRD4 (0.59) | MEN1KMT2AALDH1A1CYP1A2POLB | |
| SCHEMBL3984770 | 0.73 | SERPINE1 (0.58) | MEN1KMT2AALDH1A1CYP1A2POLB | |
| SCHEMBL3945167 | 0.73 | BRD4 (0.61) | MEN1KMT2AALDH1A1CYP1A2POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7417066-B2 | Inhibitors of soluble adenylate cyclase | SCHERING AG (DE) | 2008-08-26 | — | — | US | disclosed |