Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | MGLL | Q99685 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14079963 | 0.92 | ALDH1A1 (0.41) | ALDH1A1L3MBTL1KDM4EMGLLGAA | |
| SCHEMBL9275287 | 0.87 | ALDH1A1 (0.39) | ALDH1A1L3MBTL1KDM4EMGLLGAA | |
| SCHEMBL1515242 | 0.87 | ALDH1A1 (0.39) | ALDH1A1L3MBTL1KDM4EMGLLGAA | |
| SCHEMBL3652178 | 0.85 | ALDH1A1 (0.38) | ALDH1A1L3MBTL1KDM4EMGLLGAA | |
| SCHEMBL3756826 | 0.85 | ALDH1A1 (0.38) | ALDH1A1L3MBTL1KDM4EMGLLGAA | |
| SCHEMBL14079934 | 0.85 | KDM4E (0.35) | ALDH1A1L3MBTL1KDM4ENPSR1 | |
| SCHEMBL12774148 | 0.83 | ALDH1A1 (0.37) | ALDH1A1L3MBTL1KDM4EMGLLGAA | |
| SCHEMBL24402051 | 0.81 | ALDH1A1 (0.36) | ALDH1A1MGLLPIK3CD | |
| SCHEMBL20211307 | 0.81 | ALDH1A1 (0.36) | ALDH1A1MGLLPIK3CD | |
| SCHEMBL522388 | 0.81 | ALDH1A1 (0.36) | ALDH1A1KDM4EMGLLGAAPIK3CD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080200433-A1 | Molecular Chaperone Function Regulator | MITSUBISHI TANABE PHARMA CORPORATION (JP) | 2008-08-21 | — | — | US | disclosed |
| US-20080200433-A1 | Molecular Chaperone Function Regulator | MITSUBISHI TANABE PHARMA CORPORATION (JP) | 2008-08-21 | — | — | US | disclosed |
| US-20070265260-A1 | Quinazoline derivatives | MITSUBISHI TANABE PHARMA CORPORATION (JP) | 2007-11-15 | — | — | US | disclosed |
| US-7294629-B2 | Quinazoline derivatives | MITSUBISHI PHARMA CORPORATION (JP) | 2007-11-13 | — | — | US | disclosed |
| US-7294629-B2 | Quinazoline derivatives | MITSUBISHI PHARMA CORPORATION (JP) | 2007-11-13 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070265260-A1 | Quinazoline derivatives | TYK2, ROR1, JAK1 | ALDH1A1 3381/4885L3MBTL1 3540/4885KDM4E 2465/4885 |
| US-20080200433-A1 | Molecular Chaperone Function Regulator | HSPBP1, HSF1, HSPH1 | ALDH1A1 2634/4885L3MBTL1 2716/4885KDM4E 3574/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.