Sugi Predict

Sugi Predict / Compounds / SCHEMBL14080195

SCHEMBL14080195

SCHEMBL14080195

CCCC(=O)N1CCCC1C=O

nearest known ligand 0.48

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
▸ DPP4 P27487 5/20 0.40
▸ HCRTR2 O43614 1/20 0.40
▸ MEN1 O00255 1/20 0.38
▸ POLB P06746 1/20 0.38
▸ MAPT P10636 1/20 0.38
▸ KMT2A Q03164 1/20 0.38
▸ ACE P12821 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21339701 0.87 L3MBTL1 (0.49) DPP4MEN1POLBMAPTKMT2A
SCHEMBL8268637 0.87 L3MBTL1 (0.49) DPP4MEN1POLBMAPTKMT2A
SCHEMBL14273591 0.85 DPP4 (0.41) DPP4MEN1POLBKMT2A
SCHEMBL12324861 0.85 DPP4 (0.41) DPP4MEN1POLBKMT2A
SCHEMBL11432958 0.82 ACE (0.41) POLBACE
SCHEMBL6389769 0.82 ACE (0.41) POLBACE
SCHEMBL14453256 0.81 ACE (0.40) DPP4HCRTR2ACE
SCHEMBL27581728 0.81 L3MBTL1 (0.53) MEN1MAPTKMT2A
SCHEMBL24693976 0.81 POLB (0.34) DPP4MEN1POLBMAPTKMT2A
SCHEMBL28780658 0.80 EPHX2 (0.39) DPP4MEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2008106224-A1 MACROLIDE COMPOUNDS AND METHODS OF MAKING AND USING THE SAME RIB-X PHARMACEUTICALS, INC. (US) 2008-09-04 — — WO disclosed
WO-2008106204-A1 MACROLIDE COMPOUNDS AND METHODS OF MAKING AND USING THE SAME RIB-X-PHARMACEUTICALS, INC. (US) 2008-09-04 — — WO disclosed
Send feedback