Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.49 |
| ▸ | GNAI3 | P08754 | 7/20 | 0.48 |
| ▸ | GNAO1 | P09471 | 7/20 | 0.48 |
| ▸ | GNAI1 | P63096 | 7/20 | 0.48 |
| ▸ | MEN1 | O00255 | 2/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
| ▸ | DPP4 | P27487 | 2/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21339701 | 1.00 | L3MBTL1 (0.49) | L3MBTL1GNAI3GNAO1GNAI1MEN1 | |
| SCHEMBL27581728 | 0.94 | L3MBTL1 (0.53) | L3MBTL1GNAI3GNAO1GNAI1MEN1 | |
| SCHEMBL20415541 | 0.89 | ALDH1A1 (0.50) | L3MBTL1TDP1 | |
| SCHEMBL14080195 | 0.87 | DPP4 (0.40) | MEN1KMT2ADPP4POLBMAPT | |
| SCHEMBL6382969 | 0.82 | ABCC4 (0.42) | DPP4MAPT | |
| SCHEMBL30110380 | 0.81 | L3MBTL1 (0.51) | L3MBTL1GNAI3GNAO1GNAI1MEN1 | |
| SCHEMBL28090510 | 0.81 | L3MBTL1 (0.45) | L3MBTL1GNAI3GNAO1GNAI1MEN1 | |
| SCHEMBL14273591 | 0.80 | DPP4 (0.41) | L3MBTL1MEN1KMT2ADPP4POLB | |
| SCHEMBL12324861 | 0.80 | DPP4 (0.41) | L3MBTL1MEN1KMT2ADPP4POLB | |
| SCHEMBL16677200 | 0.79 | MEN1 (0.56) | L3MBTL1GNAI3GNAO1GNAI1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2006043145-A1 | INHIBITORS OF HEPATITIS C VIRUS PROTEASE, AND COMPOSITIONS AND TREATMENTS USING THE SAME | PFIZER INC. (US) | 2006-04-27 | — | — | WO | disclosed |