Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 9/20 | 0.44 |
| ▸ | DCTPP1 | Q9H773 | 3/20 | 0.44 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | RAB9A | P51151 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11943590 | 0.88 | ALDH1A1 (0.47) | ALDH1A1DCTPP1RXFP1SMN1; SMN2MAPT | |
| SCHEMBL11943540 | 0.87 | ALDH1A1 (0.45) | ALDH1A1DCTPP1RXFP1SMN1; SMN2MAPT | |
| SCHEMBL11943581 | 0.87 | ALDH1A1 (0.46) | ALDH1A1DCTPP1RXFP1SMN1; SMN2MAPT | |
| SCHEMBL11943588 | 0.86 | ALDH1A1 (0.49) | ALDH1A1DCTPP1RXFP1SMN1; SMN2MAPT | |
| SCHEMBL11943258 | 0.85 | ALDH1A1 (0.45) | ALDH1A1DCTPP1RXFP1SMN1; SMN2MAPT | |
| SCHEMBL14899775 | 0.85 | SIGMAR1 (0.46) | ALDH1A1DCTPP1RXFP1SMN1; SMN2MAPT | |
| SCHEMBL11943584 | 0.83 | ALDH1A1 (0.46) | ALDH1A1DCTPP1RXFP1SMN1; SMN2MAPT | |
| SCHEMBL11943583 | 0.83 | ALDH1A1 (0.47) | ALDH1A1DCTPP1RXFP1SMN1; SMN2MAPT | |
| SCHEMBL13304479 | 0.83 | SMN1; SMN2 (0.55) | ALDH1A1DCTPP1RXFP1SMN1; SMN2MAPT | |
| SCHEMBL13304382 | 0.80 | ALDH1A1 (0.46) | ALDH1A1DCTPP1RXFP1SMN1; SMN2MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008115381-A1 | PYRIDAZINONE DERIVATIVES USEFUL AS GLUCAN SYNTHASE INHIBITORS | SCHERING CORPORATION (US) | 2008-09-25 | — | — | WO | disclosed |