SCHEMBL140832

SCHEMBL140832

CCCCCCC1=Cc2c(-c3cccc4ccccc34)cccc2C1[Zr](Cl)(Cl)(C1C(CCCCCC)=Cc2c(-c3cccc4ccccc34)cccc21)[SiH](C)C

nearest known ligand 0.39

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
CNR1 P21554 2/20 0.39
ALOX15 P16050 3/20 0.33
TLR8 Q9NR97 1/20 0.32
CNR2 P34972 1/20 0.32
MAPT P10636 2/20 0.31
DRD2 P14416 1/20 0.31
SLC6A2 P23975 1/20 0.31
HTR2A P28223 1/20 0.31
HTR2C P28335 1/20 0.31
SLC6A4 P31645 1/20 0.31
PTPN1 P18031 1/20 0.30
KCNH2 Q12809 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL141430 0.99 CNR1 (0.38) CNR1ALOX15TLR8CNR2
SCHEMBL141781 0.96 CNR1 (0.34) CNR1ALOX15TLR8CNR2DRD2
SCHEMBL5890481 0.95 CNR1 (0.33) CNR1ALOX15TLR8CNR2
SCHEMBL138392 0.91 ALOX15 (0.32) CNR1ALOX15DRD2SLC6A4
SCHEMBL5890108 0.90 ALOX15 (0.31) CNR1ALOX15DRD2SLC6A4
SCHEMBL688919 0.88 CNR1 (0.40) CNR1ALOX15TLR8CNR2MAPT
SCHEMBL690807 0.88 CNR1 (0.40) CNR1ALOX15TLR8CNR2MAPT
SCHEMBL691018 0.87 CNR1 (0.39) CNR1ALOX15TLR8CNR2
SCHEMBL138908 0.87 ALOX15 (0.31) ALOX15
SCHEMBL139034 0.86 CNR1 (0.33) CNR1PTPN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-102356100-B Copolymer of olefin and conjugated diene and preparation method thereof MITSU CHEMICALS INC 2014-01-08 CN disclosed
US-8513368-B2 Copolymer of olefin and conjugated diene, and process for producing the same MITSUI CHEMICALS, INC. (JP) 2013-08-20 US disclosed
US-20120059135-A1 COPOLYMER OF OLEFIN AND CONJUGATED DIENE, AND PROCESS FOR PRODUCING THE SAME MITSUI CHEMICALS, INC. (JP) 2012-03-08 US disclosed
EP-1070729-B1 Transition metal compound, olefin polymerization catalyst component comprising said compound, olefin polymerization catalyst containing said component, process for olefin polymerization using said catalyst, propylene homopolymer, propylene copolymer and propylene elastomer MITSUI CHEMICALS INC (JP) 2011-09-28 EP disclosed
EP-0812854-B2 Novel transition metal compound, olefin polymerization catalyst comprising said compound, process for olefin polymerization using said catalyst and propylene homo- and copolymer MITSUI CHEMICALS INC (JP) 2011-04-20 EP disclosed
EP-0812854-B1 Novel transition metal compound, olefin polymerization catalyst comprising said compound, process for olefin polymerization using said catalyst and propylene homo- and copolymer MITSUI CHEMICALS INC (JP) 2001-08-16 EP disclosed
EP-1070729-A2 Transition metal compound, olefin polymerization catalyst component comprising said compound, olefin polymerization catalyst containing said component, process for olefin polymerization using said catalyst, propylene homopolymer, propylene copolymer and propylene elastomer Mitsui Chemicals, Inc. (JP) 2001-01-24 EP disclosed
US-5936053-A RIGIDITY, HEAT RESISTANCE, IMPACT STRENGTH; LOW PROPORTION OF INVERSELY INSERTED PROPYLENE UNITS MITSUI CHEMICALS, INC. (JP) 1999-08-10 US disclosed
US-5723640-A Transition metal compound having indenyl-containing metallocene MITSUI PETROCHEMICAL INDUSTRIES, LTD. (JP) 1998-03-03 US disclosed
US-5710223-A COORDINATION POLYMERIZATION CATALYSTS FOR PROPYLENE HOMOPOLYMERS AND COPOLYMERS MITSUI PETROCHEMICAL INDUSTRIES LTD. (JP) 1998-01-20 US disclosed
US-5705584-A COORDINATION CATALYSTS FOR ADDITION POLYMERIZATION OF PROPYLENE MITSUI PETROCHEMICAL INDUSTRIES, LTD. (JP) 1998-01-06 US disclosed
EP-0812854-A2 Novel transition metal compound, olefin polymerization catalyst comprising said compound, process for olefin polymerization using said catalyst and propylene homo- and copolymer MITSUI PETROCHEMICAL INDUSTRIES, LTD. (JP) 1997-12-17 EP disclosed
US-5658997-A USING ZIRCONIUM COMPOUND WITH ALUMINOXANE AND ORGANOALUMINUM COMPOUND MITSUI PETROCHEMICAL INDUSTRIES, LTD. (JP) 1997-08-19 US disclosed
US-5629254-A Substituted indenyl ring containing metallocene catalyst for propylene polymerization process MITSUI PETROCHEMICAL INDUSTRIES CO., LTD. (JP) 1997-05-13 US disclosed
EP-0629632-A2 Novel transition metal compound for use as a polymerization catalyst MITSUI PETROCHEMICAL INDUSTRIES, LTD. (JP) 1994-12-21 EP disclosed