SCHEMBL138392

SCHEMBL138392

CCCC1=Cc2c(-c3cccc4ccccc34)cccc2C1[Zr](Cl)(Cl)(C1C(CCC)=Cc2c(-c3cccc4ccccc34)cccc21)[SiH](C)C

nearest known ligand 0.32

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
ALOX15 P16050 2/20 0.32
HTR7 P34969 1/20 0.31
SLC6A4 P31645 2/20 0.31
DRD2 P14416 1/20 0.31
CNR1 P21554 2/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5890108 0.99 ALOX15 (0.31) ALOX15HTR7SLC6A4DRD2CNR1
SCHEMBL141781 0.93 CNR1 (0.34) ALOX15HTR7SLC6A4DRD2CNR1
SCHEMBL5890481 0.92 CNR1 (0.33) ALOX15CNR1
SCHEMBL141430 0.92 CNR1 (0.38) ALOX15CNR1
SCHEMBL140832 0.91 CNR1 (0.39) ALOX15SLC6A4DRD2CNR1
SCHEMBL138908 0.91 ALOX15 (0.31) ALOX15HTR7
SCHEMBL25221304 0.90 ALDH1A1 (0.31)
SCHEMBL138153 0.88 ALOX15 (0.30) ALOX15
SCHEMBL139103 0.88 HTR1A (0.31) HTR7
SCHEMBL689432 0.87 CNR1 (0.32) ALOX15HTR7CNR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 151 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7618912-B2 Preparation of supported catalyst systems BASELL POLYOLEFINE GMBH (DE) 2009-11-17 US claimed
US-20060166813-A1 Preparation of supported catalyst systems BASELL POLYOLEFINE GMBH (DE) 2006-07-27 US claimed
EP-2576642-B1 PROCESS FOR PREPARING A SUPPORTED CATALYST SYSTEM FOR OLEFIN POLYMERIZATION, THE CATALYST SYSTEM AND ITS USE BASELL POLYOLEFINE GMBH (DE) 2017-08-16 EP disclosed
EP-2513166-B1 PROCESS FOR THE PREPARATION OF SUPPORTED CATALYSTS BASELL POLYOLEFINE GMBH (DE) 2017-04-05 EP disclosed
EP-1824888-B1 MONOCYCLOPENTADIENYL COMPLEXES BASELL POLYOLEFINE GMBH (DE) 2017-01-18 EP disclosed
US-8999875-B2 Process for preparing a supported catalyst system for olefin polymerization, the catalyst system and its use BASELL POLYOLEFINE GMBH (DE) 2015-04-07 US disclosed
EP-2415792-B1 COPOLYMER OF OLEFIN AND CONJUGATED DIENE, AND PROCESS FOR PRODUCING SAME MITSUI CHEMICALS INC (JP) 2014-11-12 EP disclosed
EP-1740626-B1 CATALYST SYSTEM FOR OLEFIN POLYMERIZATION, ITS PRODUCTION AND USE BASELL POLYOLEFINE GMBH (DE) 2014-10-22 EP disclosed
US-8859451-B2 Process for the preparation of supported catalysts BASELL POLYOLEFINE GMBH (DE) 2014-10-14 US disclosed
US-8680001-B2 Preparation of supported catalyst systems containing reduced amounts of aluminoxanes BASELL POLYOLEFINE GMBH (DE) 2014-03-25 US disclosed
US-8664140-B2 Catalyst system for olefin polymerization, its production and use BASELL POLYOLEFINE GMBH (DE) 2014-03-04 US disclosed
US-5840950-A Process for converting the achiral meso form or the racemate of an ansa-metallocene complex or mixtures thereof into one of its enantiomers BASF AKTIENGESELLSCHAFT (DE) 1998-11-24 US disclosed
CN-1190399-A Process for converting achiral meso form or racemate of ansa-metallocene complex or mixtures thereof into one of its enantiomers BASF AG (DE) 1998-08-12 CN disclosed
US-5723640-A Transition metal compound having indenyl-containing metallocene MITSUI PETROCHEMICAL INDUSTRIES, LTD. (JP) 1998-03-03 US disclosed
US-5710223-A COORDINATION POLYMERIZATION CATALYSTS FOR PROPYLENE HOMOPOLYMERS AND COPOLYMERS MITSUI PETROCHEMICAL INDUSTRIES LTD. (JP) 1998-01-20 US disclosed
US-5705584-A COORDINATION CATALYSTS FOR ADDITION POLYMERIZATION OF PROPYLENE MITSUI PETROCHEMICAL INDUSTRIES, LTD. (JP) 1998-01-06 US disclosed
EP-0812854-A2 Novel transition metal compound, olefin polymerization catalyst comprising said compound, process for olefin polymerization using said catalyst and propylene homo- and copolymer MITSUI PETROCHEMICAL INDUSTRIES, LTD. (JP) 1997-12-17 EP disclosed
US-5658997-A USING ZIRCONIUM COMPOUND WITH ALUMINOXANE AND ORGANOALUMINUM COMPOUND MITSUI PETROCHEMICAL INDUSTRIES, LTD. (JP) 1997-08-19 US disclosed
US-5629254-A Substituted indenyl ring containing metallocene catalyst for propylene polymerization process MITSUI PETROCHEMICAL INDUSTRIES CO., LTD. (JP) 1997-05-13 US disclosed
EP-0629632-A2 Novel transition metal compound for use as a polymerization catalyst MITSUI PETROCHEMICAL INDUSTRIES, LTD. (JP) 1994-12-21 EP disclosed