Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE2A | O00408 | 3/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13527749 | 0.91 | RXRA (0.33) | — | |
| SCHEMBL14082448 | 0.89 | CREBBP (0.33) | — | |
| SCHEMBL14083246 | 0.88 | — | — | |
| SCHEMBL14083227 | 0.85 | HIF1A (0.31) | — | |
| SCHEMBL20026339 | 0.85 | HIF1A (0.33) | — | |
| SCHEMBL13527721 | 0.85 | HIF1A (0.33) | — | |
| SCHEMBL13527720 | 0.84 | HTT (0.33) | — | |
| SCHEMBL20026108 | 0.84 | HTT (0.33) | — | |
| SCHEMBL13527623 | 0.83 | ALDH1A1 (0.37) | — | |
| SCHEMBL14082954 | 0.83 | ACACB (0.31) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008106224-A1 | MACROLIDE COMPOUNDS AND METHODS OF MAKING AND USING THE SAME | RIB-X PHARMACEUTICALS, INC. (US) | 2008-09-04 | — | — | WO | disclosed |