SCHEMBL1408418

SCHEMBL1408418

C=Cc1ccc(C(CO)CCC)cc1

nearest known ligand 0.46

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
TAS1R3 Q7RTX0 2/20 0.46
TAS1R1 Q7RTX1 2/20 0.46
ESR1 P03372 2/20 0.42
ESR2 Q92731 2/20 0.42
ALDH1A1 P00352 3/20 0.39
CHRNB2 P17787 1/20 0.33
CHRNB4 P30926 1/20 0.33
CHRNA3 P32297 1/20 0.33
CHRNA7 P36544 1/20 0.33
CHRNA4 P43681 1/20 0.33
TDP1 Q9NUW8 1/20 0.32
HDAC8 Q9BY41 1/20 0.31
TSHR P16473 2/20 0.31
AOC3 Q16853 1/20 0.31
GRIA4 P48058 1/20 0.31
LMNA P02545 1/20 0.31
KMT2A Q03164 1/20 0.30
SPHK1 Q9NYA1 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1408257 0.88 NR1I2 (0.40) TAS1R3TAS1R1ESR1ESR2ALDH1A1
SCHEMBL16407305 0.85 ALDH1A1 (0.42) TAS1R3TAS1R1ESR1ESR2ALDH1A1
SCHEMBL5034586 0.85 TAS1R3 (0.45) TAS1R3TAS1R1ESR1ESR2ALDH1A1
SCHEMBL1207977 0.85 ALDH1A1 (0.50) TAS1R3TAS1R1ALDH1A1CHRNB2CHRNB4
SCHEMBL5133124 0.79 TAS1R3 (0.50) TAS1R3TAS1R1ESR1ESR2ALDH1A1
SCHEMBL1140695 0.77 TAS1R3 (0.47) TAS1R3TAS1R1ESR1ESR2ALDH1A1
SCHEMBL11215658 0.77 ALDH1A1 (0.50) TAS1R3TAS1R1ESR1ESR2ALDH1A1
SCHEMBL5024850 0.76 TAS1R3 (0.46) TAS1R3TAS1R1ESR1ESR2ALDH1A1
SCHEMBL11851593 0.76 ESR1 (0.46) ESR1ESR2ALDH1A1AOC3KMT2A
SCHEMBL11854403 0.76 ESR1 (0.46) ESR1ESR2TSHRAOC3LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 20 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
JP-3296066-A None JP disclosed
EP-2296058-B1 Image forming apparatus RICOH CO LTD (JP) 2018-08-01 EP disclosed
CN-108227417-A Toner 佳能株式会社 2018-06-29 CN disclosed
CN-104133355-B Developer supply container and developer compensation process 佳能株式会社 2018-06-29 CN disclosed
CN-104133351-B Toner and image forming method 佳能株式会社 2018-05-11 CN disclosed
CN-107924151-A The charge control agent and toner of pyrazolone derivative or the salt of the derivative are used 保土谷化学工业株式会社 2018-04-17 CN disclosed
CN-104345595-B Toner 佳能株式会社 2018-04-03 CN disclosed
CN-107209466-A Toner, toner accepting unit and image forming apparatus 株式会社理光 2017-09-26 CN disclosed
CN-107015450-A Toner, image forming apparatus and image forming method 佳能株式会社 2017-08-04 CN disclosed
CN-104024950-B Magnetic toner 佳能株式会社 2017-05-24 CN disclosed
CN-106537258-A Toner, image forming apparatus, image forming method, and process cartridge 株式会社理光 2017-03-22 CN disclosed
US-8364065-B2 Image forming apparatus and image forming system RICOH COMPANY, LTD. (JP) 2013-01-29 US disclosed
US-8257898-B2 Method of manufacturing a toner, device of manufacturing a toner, and toner RICOH COMPANY, LTD. (JP) 2012-09-04 US disclosed
US-20110064489-A1 Image forming apparatus and image forming system RICOH COMPANY, LTD. 2011-03-17 US disclosed
EP-2296058-A2 Image forming apparatus and image forming system Ricoh Company, Ltd. (JP) 2011-03-16 EP disclosed
US-20100055600-A1 METHOD OF MANUFACTURING A TONER, DEVICE OF MANUFACTURING A TONER, AND TONER RICOH COMPANY, LTD. (JP) 2010-03-04 US disclosed
US-7361441-B2 Color toner, and full-color image-forming method CANON KABUSHIKI KAISHA (JP) 2008-04-22 US disclosed
US-20070031747-A1 Color toner, and full-color image-forming method CANON KABUSHIKI KAISHA (JP) 2007-02-08 US disclosed
EP-1176473-A2 Toner, image forming method, and process cartridge CANON KABUSHIKI KAISHA (JP) 2002-01-30 EP disclosed
JP-H03296066-A ELECTROSTATIC CHARGE IMAGE DEVELOPING TONER FUJI XEROX CO LTD 1991-12-26 JP disclosed