SCHEMBL14084608

SCHEMBL14084608

O=C(O)Sc1nc(Cl)nc(Nc2ccc3c(O)c(N=Nc4ccc(C(=O)Nc5cccc(SC#COOS(=O)(=O)O)c5)cc4)c(SOOO)cc3c2)n1

nearest known ligand 0.38

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
▸ PRMT1 Q99873 2/20 0.38
▸ CARM1 Q86X55 1/20 0.38
▸ ENPP2 Q13822 2/20 0.33
▸ PRMT3 O60678 1/20 0.32
▸ EP300 Q09472 1/20 0.32
▸ PRMT6 Q96LA8 1/20 0.32
▸ PHLPP2 Q6ZVD8 1/20 0.32
▸ MEN1 O00255 1/20 0.30
▸ MAPT P10636 1/20 0.30
▸ HTT P42858 1/20 0.30
▸ KMT2A Q03164 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14020337 0.93 PRMT1 (0.37) PRMT1CARM1ENPP2PRMT3EP300
SCHEMBL14084614 0.91 PRMT1 (0.41) PRMT1CARM1ENPP2PRMT3EP300
SCHEMBL14020342 0.84 PRMT1 (0.40) PRMT1CARM1ENPP2PRMT3EP300
SCHEMBL14084623 0.80 CARM1 (0.37) PRMT1CARM1
SCHEMBL14020351 0.80 CARM1 (0.38) PRMT1CARM1ENPP2
SCHEMBL14084607 0.79 CARM1 (0.37) PRMT1CARM1ENPP2
SCHEMBL14020338 0.79 CARM1 (0.38) PRMT1CARM1ENPP2
SCHEMBL14084628 0.77 FUT8 (0.35) PRMT1CARM1ENPP2
SCHEMBL14084609 0.77 CARM1 (0.34) PRMT1CARM1ENPP2
SCHEMBL14084622 0.74 FUT8 (0.44) —

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20080207881-A1 Reactive dyes containing an alkylthio-s-triazinyl reactive group EVERLIGHT USA, INC. (US) 2008-08-28 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20080207881-A1 Reactive dyes containing an alkylthio-s-triazinyl reactive group TST, IK, NOX5 PRMT1 496/4885CARM1 365/4885ENPP2 2713/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

Send feedback