SCHEMBL14084615

SCHEMBL14084615

C=COOSc1ccc(N=Nc2c(SOOO)cc3cc(S(=O)(=O)O)cc(Nc4nc(Cl)nc(SO)n4)c3c2O)c(OC)c1

nearest known ligand 0.42

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
▸ FUT8 Q9BYC5 1/20 0.42
▸ ENPP2 Q13822 2/20 0.36
▸ PRMT1 Q99873 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14020346 0.96 FUT8 (0.42) FUT8ENPP2PRMT1
SCHEMBL14084620 0.79 FUT8 (0.39) FUT8ENPP2
SCHEMBL14084619 0.78 FUT8 (0.46) FUT8ENPP2
SCHEMBL14084627 0.78 FUT8 (0.42) FUT8
SCHEMBL14084618 0.76 FUT8 (0.44) FUT8ENPP2PRMT1
SCHEMBL14084616 0.76 FUT8 (0.42) FUT8
SCHEMBL14020349 0.75 FUT8 (0.39) FUT8ENPP2
SCHEMBL14020359 0.75 FUT8 (0.42) FUT8
SCHEMBL14071634 0.74 FUT8 (0.52) FUT8ENPP2PRMT1
SCHEMBL14020931 0.74 FUT8 (0.52) FUT8ENPP2PRMT1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20080207881-A1 Reactive dyes containing an alkylthio-s-triazinyl reactive group EVERLIGHT USA, INC. (US) 2008-08-28 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20080207881-A1 Reactive dyes containing an alkylthio-s-triazinyl reactive group TST, IK, NOX5 FUT8 672/4885ENPP2 2713/4885PRMT1 496/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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