Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN1 | P18031 | 3/20 | 0.55 |
| ▸ | CES2 | O00748 | 1/20 | 0.55 |
| ▸ | TOP2A | P11388 | 1/20 | 0.55 |
| ▸ | CES1 | P23141 | 1/20 | 0.55 |
| ▸ | PTGES | O14684 | 2/20 | 0.53 |
| ▸ | GPBAR1 | Q8TDU6 | 4/20 | 0.47 |
| ▸ | LMNA | P02545 | 2/20 | 0.47 |
| ▸ | NT5E | P21589 | 2/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | GLI1 | P08151 | 3/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | ATM | Q13315 | 1/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
| ▸ | RELA | Q04206 | 1/20 | 0.43 |
| ▸ | RORC | P51449 | 2/20 | 0.42 |
| ▸ | EGLN2 | Q96KS0 | 5/20 | 0.42 |
| ▸ | EGLN1 | Q9GZT9 | 5/20 | 0.42 |
| ▸ | EGLN3 | Q9H6Z9 | 5/20 | 0.42 |
| ▸ | P4HTM | Q9NXG6 | 5/20 | 0.42 |
| ▸ | ALB | P02768 | 2/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10081999 | 0.86 | PTPN1 (0.52) | PTPN1CES2TOP2ACES1PTGES | |
| SCHEMBL7747717 | 0.86 | LMNA (0.58) | PTPN1CES2TOP2ACES1PTGES | |
| SCHEMBL6119147 | 0.86 | GPBAR1 (0.65) | PTPN1CES2CES1GPBAR1LMNA | |
| SCHEMBL6715660 | 0.86 | LMNA (0.58) | PTPN1CES2TOP2ACES1PTGES | |
| Glochidone SCHEMBL31721106 | 0.82 | PTPN1 (0.56) | PTPN1CES2TOP2ACES1PTGES | |
| SCHEMBL6112667 | 0.79 | GPBAR1 (0.47) | PTPN1GPBAR1LMNANT5ESMN1; SMN2 | |
| Lupenone SCHEMBL1224027 | 0.77 | GPBAR1 (0.75) | PTPN1CES2TOP2ACES1PTGES | |
| Lupenone SCHEMBL13908727 | 0.77 | GPBAR1 (0.75) | PTPN1CES2TOP2ACES1PTGES | |
| Lupenone SCHEMBL13851777 | 0.77 | GPBAR1 (0.75) | PTPN1CES2TOP2ACES1PTGES | |
| Lupenone SCHEMBL13692854 | 0.77 | GPBAR1 (0.75) | PTPN1CES2TOP2ACES1PTGES |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7410958-B2 | Triterpene quaternary salts as biologically active surfactants | REGENTS OF THE UNIVERSITY OF MINNESOTA (US) | 2008-08-12 | — | — | US | disclosed |
| US-20070259839-A1 | TRITERPENE QUATERNARY SALTS AS BIOLOGICALLY ACTIVE SURFACTANTS | REGENTS OF THE UNIVERSITY OF MINNESOTA | 2007-11-08 | — | — | US | disclosed |
| US-20070259842-A1 | TRITERPENE QUATERNARY SALTS AS BIOLOGICALLY ACTIVE SURFACTANTS | REGENTS OF THE UNIVERSITY OF MINNESOTA | 2007-11-08 | — | — | US | disclosed |
| US-20070088009-A1 | TRITERPENE QUATERNARY SALTS AS BIOLOGICALLY ACTIVE SURFACTANTS | KRASUTSKY PAVEL A | 2007-04-19 | — | — | US | disclosed |
| US-7199114-B2 | Triterpene quaternary salts as biologically active surfactants | THE REGENTS OF THE UNIVERSITY OF MINNESOTA (US) | 2007-04-03 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070259842-A1 | TRITERPENE QUATERNARY SALTS AS BIOLOGICALLY ACTIVE SURFACTANTS | BET1, PGGT1B, RABGGTB | PTPN1 2823/4885CES2 2548/4885TOP2A 437/4885 |
| US-20070259839-A1 | TRITERPENE QUATERNARY SALTS AS BIOLOGICALLY ACTIVE SURFACTANTS | BET1, PGGT1B, RABGGTB | PTPN1 2823/4885CES2 2548/4885TOP2A 437/4885 |
| US-20070088009-A1 | TRITERPENE QUATERNARY SALTS AS BIOLOGICALLY ACTIVE SURFACTANTS | BET1, PGGT1B, RABGGTB | PTPN1 2823/4885CES2 2548/4885TOP2A 437/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.