⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4087414 | 1.00 | — | — | |
| SCHEMBL4772315 | 0.94 | — | — | |
| SCHEMBL12386211 | 0.91 | DUT (0.30) | — | |
| SCHEMBL7093044 | 0.91 | DUT (0.30) | — | |
| SCHEMBL7067321 | 0.90 | TK2 (0.34) | — | |
| SCHEMBL5861676 | 0.90 | TK2 (0.34) | — | |
| SCHEMBL5557385 | 0.90 | TK2 (0.34) | — | |
| SCHEMBL2768845 | 0.90 | TK2 (0.34) | — | |
| SCHEMBL1099028 | 0.90 | TK2 (0.34) | — | |
| SCHEMBL5878736 | 0.90 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1013661-B2 | 2'-O,4'-C-methylene bicyclonucleosides | EXIQON AS (DK) | 2018-10-24 | — | — | EP | disclosed |
| EP-2361921-B1 | Bicyclo-oligonucleotide analogues | EXIQON AS (DK) | 2015-06-03 | — | — | EP | disclosed |
| EP-2295441-B1 | Bicyclonucleoside Oligonucleotide Analogue | EXIQON AS (DK) | 2014-05-07 | — | — | EP | disclosed |
| EP-1013661-B1 | 2'-O,4'-C-methylene bicyclonucleosides | EXIQON AS (DK) | 2012-01-18 | — | — | EP | disclosed |
| EP-2361921-A2 | Novel bicyclonucleoside and oligonnucleotide analogue | Exiqon A/S (DK) | 2011-08-31 | — | — | EP | disclosed |
| EP-2295441-A2 | Novel Bicyclonucleoside and Oligonucleotide Analogue | Exiqon A/S (DK) | 2011-03-16 | — | — | EP | disclosed |
| US-7034133-B2 | Locked Nucleoside Analogues is a biochemical conjugate of nucleotides; as an aptamer in specific binding of antibiotics, drugs, amino acids, peptides, enzymes, saccharides, polysaccharides; heat resistance | EXIQON A/S (DK) | 2006-04-25 | — | — | US | disclosed |
| EP-1013661-A1 | NOVEL BICYCLONUCLEOSIDE AND OLIGONUCLEOTIDE ANALOGUES | Imanishi, Takeshi (JP) | 2000-06-28 | — | — | EP | disclosed |