Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR1H2 | P55055 | 1/20 | 0.34 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.31 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.31 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.31 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.31 |
| ▸ | SRC | P12931 | 4/20 | 0.30 |
| ▸ | PARP1 | P09874 | 1/20 | 0.30 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18394293 | 0.89 | ALDH1A1 (0.36) | NR1H2ABCB1ALDH1A1MEN1MAPT | |
| SCHEMBL29273310 | 0.89 | ALDH1A1 (0.36) | NR1H2ABCB1ALDH1A1MEN1MAPT | |
| SCHEMBL2080406 | 0.89 | ALDH1A1 (0.36) | NR1H2ABCB1ALDH1A1MEN1MAPT | |
| SCHEMBL17154897 | 0.89 | ALDH1A1 (0.36) | NR1H2ABCB1ALDH1A1MEN1MAPT | |
| SCHEMBL12431668 | 0.87 | NR1H2 (0.37) | NR1H2ABCB1ALDH1A1MEN1KMT2A | |
| SCHEMBL139880 | 0.86 | NR1H2 (0.42) | NR1H2ABCB1ALDH1A1MEN1KMT2A | |
| SCHEMBL1372634 | 0.86 | NR1H2 (0.42) | NR1H2ABCB1ALDH1A1MEN1KMT2A | |
| SCHEMBL20312947 | 0.86 | NR1H2 (0.42) | NR1H2ABCB1ALDH1A1MEN1KMT2A | |
| SCHEMBL21286125 | 0.86 | NR1H2 (0.42) | NR1H2ABCB1ALDH1A1MEN1KMT2A | |
| SCHEMBL19964151 | 0.86 | NR1H2 (0.42) | NR1H2ABCB1ALDH1A1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120058989-A1 | ANTIBACTERIAL FLUOROQUINOLONE ANALOGS | ACHAOGEN, INC. (US) | 2012-03-08 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120058989-A1 | ANTIBACTERIAL FLUOROQUINOLONE ANALOGS | RECQL, BLVRB, NQO2 | NR1H2 971/4885ABCB1 53/4885ALDH1A1 1678/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.