Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 13/20 | 0.46 |
| ▸ | HTT | P42858 | 2/20 | 0.46 |
| ▸ | HPGD | P15428 | 9/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 8/20 | 0.45 |
| ▸ | CASP1 | P29466 | 4/20 | 0.45 |
| ▸ | CASP7 | P55210 | 4/20 | 0.45 |
| ▸ | TSHR | P16473 | 3/20 | 0.45 |
| ▸ | CA9 | Q16790 | 3/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 13/20 | 0.44 |
| ▸ | GAA | P10253 | 5/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | MCL1 | Q07820 | 3/20 | 0.41 |
| ▸ | GLA | P06280 | 3/20 | 0.41 |
| ▸ | AKR1B1 | P15121 | 2/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | CA12 | O43570 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4925486 | 0.86 | ALDH1A1 (0.43) | ALDH1A1HTTHPGDHSD17B10CASP1 | |
| SCHEMBL4927301 | 0.78 | ALDH1A1 (0.39) | ALDH1A1HTTHPGDHSD17B10CASP1 | |
| SCHEMBL14088022 | 0.77 | KDM4E (0.44) | ALDH1A1HTTHPGDHSD17B10CASP1 | |
| SCHEMBL14088020 | 0.77 | PDE4D (0.46) | ALDH1A1HPGDHSD17B10CASP1CASP7 | |
| SCHEMBL14088023 | 0.75 | ALDH1A1 (0.41) | ALDH1A1HTTHPGDHSD17B10CASP1 | |
| SCHEMBL4922401 | 0.72 | ALDH1A1 (0.46) | ALDH1A1HTTHPGDHSD17B10CASP1 | |
| SCHEMBL4929370 | 0.70 | CA9 (0.61) | ALDH1A1HPGDHSD17B10CASP1CASP7 | |
| SCHEMBL9230035 | 0.69 | MCL1 (0.62) | ALDH1A1HTTHPGDHSD17B10CASP1 | |
| SCHEMBL4931168 | 0.68 | PDE4D (0.43) | ALDH1A1HPGDHSD17B10CASP1CASP7 | |
| SCHEMBL4929255 | 0.67 | HSD17B10 (0.55) | ALDH1A1HPGDHSD17B10CASP1CASP7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080194522-A1 | Development of Fluorogenic Substrates For Monoamine Oxidases (Mao-A and Mao-B) | TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK, THE | 2008-08-14 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080194522-A1 | Development of Fluorogenic Substrates For Monoamine Oxidases (Mao-A and Mao-B) | MAOA, MAOB, COMT | ALDH1A1 181/4885HTT 1157/4885HPGD 296/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.