Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.54 |
| ▸ | CRHBP | P24387 | 1/20 | 0.51 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.51 |
| ▸ | KLK7 | P49862 | 11/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | FAAH | O00519 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14088113 | 0.89 | TSHR (0.54) | TSHRKLK7ALDH1A1NPC1RAB9A | |
| SCHEMBL4911331 | 0.83 | CRHBP (0.69) | TSHRCRHBPCRHR2KLK7ALDH1A1 | |
| SCHEMBL11375689 | 0.80 | ESR1 (0.58) | TSHRCRHBPCRHR2KLK7ALDH1A1 | |
| SCHEMBL11460504 | 0.79 | KLK7 (0.64) | TSHRCRHBPCRHR2KLK7ALDH1A1 | |
| SCHEMBL7525118 | 0.79 | CRHBP (0.56) | TSHRCRHBPCRHR2KLK7ALDH1A1 | |
| SCHEMBL10001830 | 0.79 | TSHR (0.49) | TSHRALDH1A1NPC1RAB9A | |
| SCHEMBL14088215 | 0.78 | TSHR (0.44) | TSHRKLK7ALDH1A1NPC1RAB9A | |
| SCHEMBL14088160 | 0.78 | TSHR (0.44) | TSHRKLK7ALDH1A1NPC1RAB9A | |
| SCHEMBL14088110 | 0.77 | TDP1 (0.47) | TSHRKLK7ALDH1A1NPC1RAB9A | |
| SCHEMBL10174246 | 0.76 | ALDH1A1 (0.57) | TSHRALDH1A1NPC1RAB9AGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080193878-A1 | RESIST COMPOSITION AND PATTERN FORMING METHOD USING THE SAME | FUJIFILM CORPORATION (JP) | 2008-08-14 | — | — | US | disclosed |