Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FAAH | O00519 | 7/20 | 0.40 |
| ▸ | THRB | P10828 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.39 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.39 |
| ▸ | RELA | Q04206 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | ITGB3 | P05106 | 2/20 | 0.38 |
| ▸ | ITGA2B | P08514 | 2/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14088542 | 0.98 | FAAH (0.41) | FAAHTHRBNPC1LMNANFKB1 | |
| SCHEMBL14907444 | 0.95 | FAAH (0.39) | FAAHTHRBNPC1LMNANFKB1 | |
| SCHEMBL14907498 | 0.95 | FAAH (0.39) | FAAHTHRBNPC1LMNANFKB1 | |
| SCHEMBL14907500 | 0.87 | THRB (0.46) | FAAHTHRBNPC1LMNANFKB1 | |
| SCHEMBL14907436 | 0.87 | THRB (0.47) | FAAHTHRBNPC1LMNANFKB1 | |
| SCHEMBL14907438 | 0.87 | THRB (0.47) | FAAHTHRBNPC1LMNANFKB1 | |
| SCHEMBL9588581 | 0.86 | FAAH (0.46) | FAAHNPC1LMNANFKB1NFKB2 | |
| SCHEMBL9591306 | 0.86 | FAAH (0.46) | FAAHNPC1LMNANFKB1NFKB2 | |
| SCHEMBL9592395 | 0.86 | FAAH (0.46) | FAAHNPC1LMNANFKB1NFKB2 | |
| SCHEMBL9591044 | 0.86 | FAAH (0.46) | FAAHNPC1LMNANFKB1NFKB2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9507185-B2 | Switch element comprising a liquid crystalline medium | MERCK PATENT GMBH (DE) | 2016-11-29 | — | — | US | disclosed |
| US-9507185-B2 | Switch element comprising a liquid crystalline medium | MERCK PATENT GMBH (DE) | 2016-11-29 | — | — | US | disclosed |
| US-20140293174-A1 | SWITCH ELEMENT COMPRISING A LIQUID CRYSTALLINE MEDIUM | MERCK PATENT GMBH (DE) | 2014-10-02 | — | — | US | disclosed |
| US-20140293174-A1 | SWITCH ELEMENT COMPRISING A LIQUID CRYSTALLINE MEDIUM | MERCK PATENT GMBH (DE) | 2014-10-02 | — | — | US | disclosed |
| WO-2013060406-A1 | SWITCH ELEMENT COMPRISING A LIQUID CRYSTALLINE MEDIUM | MERCK PATENT GMBH (DE) | 2013-05-02 | — | — | WO | disclosed |
| US-7410677-B2 | Organosilicon compound-containing polymerizable liquid-crystal composition | CHISSO CORPORATION (JP) | 2008-08-12 | — | — | US | disclosed |