Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRB | P10828 | 3/20 | 0.40 |
| ▸ | P2RY10 | O00398 | 4/20 | 0.38 |
| ▸ | PPARG | P37231 | 3/20 | 0.37 |
| ▸ | PPARD | Q03181 | 1/20 | 0.37 |
| ▸ | PPARA | Q07869 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.35 |
| ▸ | CA12 | O43570 | 1/20 | 0.35 |
| ▸ | CA1 | P00915 | 1/20 | 0.35 |
| ▸ | CA2 | P00918 | 1/20 | 0.35 |
| ▸ | CA4 | P22748 | 1/20 | 0.35 |
| ▸ | CA9 | Q16790 | 1/20 | 0.35 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.35 |
| ▸ | PTGES | O14684 | 1/20 | 0.35 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.35 |
| ▸ | GPR174 | Q9BXC1 | 3/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14088569 | 0.99 | THRB (0.40) | THRBP2RY10PPARGPPARDPPARA | |
| SCHEMBL14088407 | 0.93 | THRB (0.43) | THRBP2RY10PPARGHTTALDH1A1 | |
| SCHEMBL14588364 | 0.92 | THRB (0.44) | THRBP2RY10PPARGPPARAHTT | |
| SCHEMBL12567643 | 0.89 | THRB (0.39) | THRBPPARGPPARDPPARAFFAR1 | |
| SCHEMBL14088574 | 0.87 | CA12 (0.34) | THRBPPARAALDH1A1CYP3A4TSHR | |
| SCHEMBL14088573 | 0.86 | THRB (0.35) | THRBPPARGPPARDPPARAFFAR1 | |
| SCHEMBL12110790 | 0.82 | THRB (0.40) | THRBFFAR1AKR1C3 | |
| SCHEMBL14185457 | 0.81 | THRB (0.39) | THRBPPARGPPARDPPARAFFAR1 | |
| SCHEMBL14588373 | 0.81 | ALDH1A1 (0.37) | THRBPPARAALDH1A1CYP3A4TSHR | |
| SCHEMBL14088581 | 0.81 | THRB (0.47) | THRBPPARGPPARDPPARAHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7410677-B2 | Organosilicon compound-containing polymerizable liquid-crystal composition | CHISSO CORPORATION (JP) | 2008-08-12 | — | — | US | disclosed |
| US-7410677-B2 | Organosilicon compound-containing polymerizable liquid-crystal composition | CHISSO CORPORATION (JP) | 2008-08-12 | — | — | US | disclosed |