Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPY1R | P25929 | 2/20 | 0.50 |
| ▸ | NPY2R | P49146 | 1/20 | 0.49 |
| ▸ | NPY5R | Q15761 | 1/20 | 0.49 |
| ▸ | MALT1 | Q9UDY8 | 1/20 | 0.45 |
| ▸ | CA12 | O43570 | 1/20 | 0.45 |
| ▸ | CA1 | P00915 | 1/20 | 0.45 |
| ▸ | CA2 | P00918 | 1/20 | 0.45 |
| ▸ | CA3 | P07451 | 1/20 | 0.45 |
| ▸ | CA4 | P22748 | 1/20 | 0.45 |
| ▸ | CA6 | P23280 | 1/20 | 0.45 |
| ▸ | CA5A | P35218 | 1/20 | 0.45 |
| ▸ | CA7 | P43166 | 1/20 | 0.45 |
| ▸ | CACNA1C | Q13936 | 1/20 | 0.45 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.45 |
| ▸ | CA9 | Q16790 | 1/20 | 0.45 |
| ▸ | CA13 | Q8N1Q1 | 1/20 | 0.45 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.45 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.45 |
| ▸ | PSMB1 | P20618 | 2/20 | 0.44 |
| ▸ | PSMB9 | P28065 | 2/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14115004 | 0.90 | NPY1R (0.53) | NPY1RNPY2RNPY5RMALT1PSMB1 | |
| SCHEMBL14583981 | 0.87 | KLKB1 (0.47) | NPY1RCA12CA1CA2CA3 | |
| SCHEMBL30305683 | 0.78 | MME (0.57) | CA2CTSC | |
| SCHEMBL14090279 | 0.76 | KMT2A (0.50) | MMP8 | |
| SCHEMBL30305685 | 0.76 | OPRK1 (0.61) | — | |
| SCHEMBL22604409 | 0.76 | OPRK1 (0.61) | — | |
| SCHEMBL30305684 | 0.76 | OPRK1 (0.61) | — | |
| SCHEMBL14583982 | 0.75 | GPR142 (0.45) | MMP8CTSC | |
| SCHEMBL7413310 | 0.74 | ALPI (0.61) | MMP8CTSC | |
| SCHEMBL3114367 | 0.74 | ALPI (0.61) | MMP8CTSC |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7417030-B2 | Indazole peptidomimetics as thrombin receptor antagonists | ORTHO-MCNEIL PHARMACEUTICAL, INC. (US) | 2008-08-26 | — | — | US | disclosed |