Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 14/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 8/20 | 0.39 |
| ▸ | CFTR | P13569 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 10/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.35 |
| ▸ | HPGD | P15428 | 7/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 2/20 | 0.33 |
| ▸ | RAB9A | P51151 | 2/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | GLA | P06280 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | RCE1 | Q9Y256 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14090843 | 0.81 | ALDH1A1 (0.39) | ALDH1A1HSD17B10CFTRTSHRMAPT | |
| SCHEMBL14090840 | 0.80 | ALDH1A1 (0.43) | ALDH1A1HSD17B10CFTRTSHRMAPT | |
| SCHEMBL14090854 | 0.79 | MAPT (0.42) | ALDH1A1HSD17B10CFTRTSHRMAPT | |
| SCHEMBL14090842 | 0.70 | ALDH1A1 (0.53) | ALDH1A1HSD17B10CFTRTSHRMAPT | |
| SCHEMBL14899721 | 0.69 | ALDH1A1 (0.43) | ALDH1A1HSD17B10CFTRTSHRMAPT | |
| SCHEMBL14090841 | 0.67 | ALDH1A1 (0.41) | ALDH1A1HSD17B10CFTRTSHRMAPT | |
| Anthranilamide SCHEMBL4393217 | 0.66 | ALDH1A1 (0.52) | ALDH1A1HSD17B10CFTRTSHRMAPT | |
| SCHEMBL23313200 | 0.66 | ALDH1A1 (0.51) | ALDH1A1HSD17B10CFTRTSHRMAPT | |
| SCHEMBL14088039 | 0.65 | MAPT (0.47) | ALDH1A1HSD17B10CFTRTSHRMAPT | |
| SCHEMBL20880393 | 0.65 | PTGS1 (0.40) | ALDH1A1HSD17B10CFTRTSHRMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7410951-B2 | Biologically active peptides and compositions, their use | THE UNIVERSITY OF BRITISH COLUMBIA (CA) | 2008-08-12 | — | — | US | disclosed |