Perflexane

Perflexane

SCHEMBL1409103

FC(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)F.N.N.O=[PH](O)O

nearest known ligand 0.46

Full drug profile on Sugi Atlas →

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
THRB P10828 1/20 0.46
LMNA P02545 1/20 0.40
CA2 P00918 3/20 0.39
CA1 P00915 2/20 0.39
MMP1 P03956 2/20 0.39
MMP2 P08253 2/20 0.39
MMP9 P14780 2/20 0.39
MMP8 P22894 2/20 0.39
MMP13 P45452 2/20 0.39
F2 P00734 2/20 0.34
PRSS1 P07477 2/20 0.34
PRSS2 P07478 2/20 0.34
PRSS3 P35030 2/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Phosphonic Acid SCHEMBL1408864 1.00 THRB (0.46) THRBLMNACA2CA1MMP1
Perflexane SCHEMBL1409099 1.00 THRB (0.46) THRBLMNACA2CA1MMP1
Perflexane SCHEMBL20530385 0.97 THRB (0.48) THRBLMNACA2CA1MMP1
Phosphonic Acid SCHEMBL20530381 0.97 THRB (0.48) THRBLMNACA2CA1MMP1
Phosphonic Acid SCHEMBL20530382 0.97 THRB (0.48) THRBLMNACA2CA1MMP1
Perflexane SCHEMBL20530384 0.97 THRB (0.48) THRBLMNACA2CA1MMP1
Ammonia Solution, Strong SCHEMBL22589066 0.78 LMNA (0.57) THRBLMNACA2CA1MMP1
Perflexane SCHEMBL3750523 0.78 LMNA (0.57) THRBLMNACA2CA1MMP1
SCHEMBL6053573 0.75 THRB (0.42) THRBLMNACA2CA1MMP1
Hydrochloric Acid SCHEMBL28645945 0.73 LMNA (0.53) THRBLMNACA2CA1MMP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2294121-B1 CURABLE COMPOSITION AND MOLDED ARTICLE MADE OF SAME DAIKIN IND LTD (JP) 2018-10-17 EP claimed
CN-112513174-A Composition, crosslinked rubber molded article, and fluoropolymer 大金工业株式会社 2021-03-16 CN disclosed
EP-2294121-B1 CURABLE COMPOSITION AND MOLDED ARTICLE MADE OF SAME DAIKIN IND LTD (JP) 2018-10-17 EP disclosed
EP-2331620-B1 CURABLE COMPOSITION AND MOLDED ARTICLE MADE OF SAME DAIKIN IND LTD (JP) 2012-08-15 EP disclosed
US-20110151164-A1 CURABLE COMPOSITION AND MOLDED ARTICLE MADE OF SAME DAIKIN INDUSTRIES, LTD. (JP) 2011-06-23 US disclosed
EP-2331620-A1 CURABLE COMPOSITION AND MOLDED ARTICLE MADE OF SAME Daikin Industries, Ltd. (JP) 2011-06-15 EP disclosed
US-20110112265-A1 CURABLE COMPOSITION AND MOLDED ARTICLE MADE OF SAME DAIKIN INDUSTRIES LTD. (JP) 2011-05-12 US disclosed
EP-2294121-A1 CURABLE COMPOSITION AND MOLDED ARTICLE MADE OF SAME Daikin Industries, Ltd. (JP) 2011-03-16 EP disclosed
WO-2010035854-A1 CURABLE COMPOSITION AND MOLDED ARTICLE MADE OF SAME DAIKIN INDUSTRIES, LTD. (JP) 2010-04-01 WO disclosed
WO-2010002013-A1 CURABLE COMPOSITION AND MOLDED ARTICLE MADE OF SAME DAIKIN INDUSTRIES, LTD. (JP) 2010-01-07 WO disclosed