Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR3C1 | P04150 | 8/20 | 0.71 |
| ▸ | GLUL | P15104 | 3/20 | 0.71 |
| ▸ | PGR | P06401 | 1/20 | 0.66 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13376552 | 0.93 | NR3C1 (0.68) | NR3C1GLUL | |
| SCHEMBL13376688 | 0.93 | NR3C1 (0.68) | NR3C1GLUL | |
| SCHEMBL14115979 | 0.93 | NR3C1 (0.68) | NR3C1GLUL | |
| SCHEMBL12671487 | 0.84 | NR3C1 (0.68) | NR3C1GLUL | |
| SCHEMBL1880341 | 0.84 | NR3C1 (0.68) | NR3C1GLUL | |
| SCHEMBL12956252 | 0.84 | NR3C1 (0.68) | NR3C1GLUL | |
| SCHEMBL14261416 | 0.84 | NR3C1 (0.71) | NR3C1GLUL | |
| SCHEMBL12956267 | 0.84 | NR3C1 (0.71) | NR3C1GLUL | |
| SCHEMBL14091722 | 0.83 | NR3C1 (0.67) | NR3C1GLUL | |
| SCHEMBL14091724 | 0.83 | NR3C1 (0.67) | NR3C1GLUL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7411073-B2 | Selective non-steroidal glucocorticoid receptor modulators | MERCK & CO., INC. (US) | 2008-08-12 | — | — | US | disclosed |
| US-7411073-B2 | Selective non-steroidal glucocorticoid receptor modulators | MERCK & CO., INC. (US) | 2008-08-12 | — | — | US | disclosed |