SCHEMBL14091725

SCHEMBL14091725

COC1C(C)OC(OC2C(O)C(CO)OC(C)C2NC(C)=O)C(O)C1O

nearest known ligand 0.47

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
▸ LGALS3 P17931 6/20 0.47
▸ LGALS8 O00214 2/20 0.47
▸ LGALS4 P56470 1/20 0.47
▸ MAPK1 P28482 2/20 0.45
▸ CD69 Q07108 1/20 0.44
▸ LGALS1 P09382 1/20 0.43
▸ LGALS7; LGALS7B P47929 1/20 0.43
▸ ALDH1A1 P00352 1/20 0.43
▸ THRB P10828 1/20 0.43
▸ LGALS9 O00182 1/20 0.42
▸ STAT3 P40763 2/20 0.40
▸ AMY2A P04746 2/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18589695 1.00 LGALS3 (0.47) LGALS3LGALS8LGALS4MAPK1CD69
SCHEMBL2602688 0.91 LGALS3 (0.49) LGALS3LGALS8LGALS4MAPK1CD69
SCHEMBL12214021 0.91 LGALS3 (0.45) LGALS3LGALS8LGALS4MAPK1CD69
SCHEMBL12213975 0.91 LGALS3 (0.45) LGALS3LGALS8LGALS4MAPK1CD69
SCHEMBL25121361 0.89 MAPK1 (0.44) LGALS3LGALS8LGALS4MAPK1CD69
SCHEMBL15215584 0.89 MAPK1 (0.44) LGALS3LGALS8LGALS4MAPK1CD69
SCHEMBL15082697 0.89 MAPK1 (0.44) LGALS3LGALS8LGALS4MAPK1CD69
SCHEMBL21374694 0.89 MAPK1 (0.44) LGALS3LGALS8LGALS4MAPK1CD69
SCHEMBL4544701 0.89 MAPK1 (0.44) LGALS3LGALS8LGALS4MAPK1CD69
SCHEMBL12213976 0.89 MAPK1 (0.44) LGALS3LGALS8LGALS4MAPK1CD69

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20150031800-A1 POLYMERIC MATERIALS INCLUDING A GLYCOSAMINOGLYCAN NETWORKED WITH A POLYOLEFIN-CONTAINING POLYMER COLORADO STATE UNIVERSITY RESEARCH FOUNDATION (US) 2015-01-29 — — US disclosed
US-20080193538-A1 Hyaluronic Acid Compound, Hydrogel Thereof and Joint Treating Material TEIJIN LIMITED (JP) 2008-08-14 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20080193538-A1 Hyaluronic Acid Compound, Hydrogel Thereof and Joint Treating Material PHOSPHO1, CD44, CUTA LGALS3 1965/4885LGALS8 2272/4885LGALS4 1286/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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