SCHEMBL14092736

SCHEMBL14092736

CCC(C)COP(=O)(O)OCC(O)CC

nearest known ligand 0.37

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
P2RY10 O00398 11/20 0.37
GPR174 Q9BXC1 10/20 0.37
GPR34 Q9UPC5 5/20 0.37
LPAR5 Q9H1C0 2/20 0.37
LPAR6 P43657 1/20 0.34
LPAR1 Q92633 1/20 0.34
LPAR4 Q99677 1/20 0.34
LPAR2 Q9HBW0 1/20 0.34
LPAR3 Q9UBY5 1/20 0.34
ENPP2 Q13822 1/20 0.34
GPR55 Q9Y2T6 1/20 0.33
PLA2G2C Q5R387 1/20 0.31
MAPT P10636 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10301404 0.90 LPAR5 (0.42) P2RY10GPR174GPR34LPAR5LPAR6
SCHEMBL2474832 0.90 LAP3 (0.36) P2RY10GPR174GPR34PLA2G2CMAPT
SCHEMBL18250368 0.84 LPAR5 (0.39) P2RY10GPR174GPR34LPAR5LPAR6
SCHEMBL12342799 0.84 PPARD (0.38) PLA2G2CMAPT
SCHEMBL13996373 0.81 PLA2G2C (0.40) P2RY10GPR34LPAR5LPAR1LPAR2
SCHEMBL28327351 0.80 P2RY10 (0.33) P2RY10
SCHEMBL15783767 0.80 PLA2G2A (0.43) PLA2G2CMAPT
SCHEMBL14366155 0.80 PLA2G2A (0.43) P2RY10GPR174GPR34LPAR5LPAR6
SCHEMBL12146347 0.79 PLA2G2C (0.48) P2RY10GPR34PLA2G2C
SCHEMBL17366005 0.78 CYP3A4 (0.45) P2RY10GPR34LPAR1LPAR2LPAR3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7413806-B2 Implant coatings BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM (US) 2008-08-19 US disclosed