Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP19A1 | P11511 | 2/20 | 0.46 |
| ▸ | LMNA | P02545 | 4/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | NPC1 | O15118 | 2/20 | 0.42 |
| ▸ | RAB9A | P51151 | 2/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | HSPB1 | P04792 | 1/20 | 0.42 |
| ▸ | CTSV | O60911 | 2/20 | 0.42 |
| ▸ | CTSL | P07711 | 2/20 | 0.42 |
| ▸ | PTGES | O14684 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 5/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | ALPG | P10696 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | PDCD1 | Q15116 | 1/20 | 0.40 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14127830 | 0.86 | CYP19A1 (0.47) | CYP19A1LMNAALDH1A1NPC1RAB9A | |
| SCHEMBL13959005 | 0.85 | PDCD1 (0.50) | CYP19A1LMNAALDH1A1NPC1RAB9A | |
| SCHEMBL4319388 | 0.81 | ALDH1A1 (0.54) | CYP19A1LMNAALDH1A1SMN1; SMN2CTSV | |
| SCHEMBL13153013 | 0.79 | ALDH1A1 (0.56) | LMNAALDH1A1SMN1; SMN2NPSR1 | |
| SCHEMBL27038529 | 0.79 | POLB (0.54) | LMNAALDH1A1NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL25986454 | 0.78 | ALDH1A1 (0.43) | LMNAALDH1A1RAB9ASMN1; SMN2MAPT | |
| SCHEMBL30069258 | 0.78 | NPC1 (0.62) | CYP19A1LMNAALDH1A1NPC1RAB9A | |
| SCHEMBL7516329 | 0.77 | NR4A2 (0.55) | LMNAALDH1A1NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL27167067 | 0.77 | POLB (0.57) | CYP19A1NPC1RAB9AHSPB1CTSV | |
| SCHEMBL30792298 | 0.74 | PTGES (0.54) | CYP19A1LMNAALDH1A1NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7408025-B2 | Lipopeptides as antibacterial agents | CUBIST PHARMACEUTICALS, INC. (US) | 2008-08-05 | — | — | US | disclosed |