SCHEMBL1409487

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL1408697	0.92	DUT (0.60)	DUTALDH1A1ATMMAPK1
	SCHEMBL21690788	0.84	ATM (0.51)	DUTALDH1A1ATMMAPK1TDP1
	SCHEMBL20254153	0.77	ALDH1A1 (0.55)	DUTALDH1A1ATMTDP1KDM4E
	SCHEMBL21690794	0.76	DUT (0.61)	DUTALDH1A1ATMTDP1KDM4E
	SCHEMBL1409473	0.74	DUT (0.47)	DUTKDM4EMAPTSMN1; SMN2KMT2A
	SCHEMBL1409471	0.74	DUT (0.47)	DUTKDM4EMAPTSMN1; SMN2KMT2A
	SCHEMBL1409084	0.74	DUT (0.88)	DUT
	SCHEMBL21690376	0.73	DUT (0.55)	DUTALDH1A1ATMTDP1KDM4E
	SCHEMBL5812323	0.73	PARG (0.62)	ALDH1A1ATMTDP1KDM4EMAPT
	SCHEMBL1409626	0.72	MAPK1 (0.70)	ALDH1A1MAPK1KDM4EMAPTSMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.