Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RXRA | P19793 | 2/20 | 0.45 |
| ▸ | RXRB | P28702 | 2/20 | 0.45 |
| ▸ | RXRG | P48443 | 2/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.44 |
| ▸ | S1PR1 | P21453 | 4/20 | 0.43 |
| ▸ | S1PR5 | Q9H228 | 1/20 | 0.42 |
| ▸ | PDE7A | Q13946 | 2/20 | 0.41 |
| ▸ | PDE3A | Q14432 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.39 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.39 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | HPGD | P15428 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | PDE4A | P27815 | 1/20 | 0.38 |
| ▸ | PTGDR2 | Q9Y5Y4 | 2/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1410091 | 0.87 | RPA1 (0.43) | RXRARXRBRXRGKDM4ELMNA | |
| SCHEMBL1410412 | 0.79 | RXRA (0.44) | RXRARXRBRXRGKDM4EALDH1A1 | |
| SCHEMBL1410151 | 0.79 | CYP1A2 (0.57) | KDM4ESMN1; SMN2ALDH1A1HPGDCYP1A2 | |
| SCHEMBL1410275 | 0.78 | RXRA (0.54) | RXRARXRBRXRGKDM4EALDH1A1 | |
| SCHEMBL1409530 | 0.77 | PSEN1 (0.42) | RXRARXRBRXRGKDM4ES1PR1 | |
| SCHEMBL1410228 | 0.77 | PDE7A (0.48) | RXRARXRBRXRGKDM4EPDE7A | |
| SCHEMBL1409349 | 0.77 | ALDH1A1 (0.47) | KDM4EPDE7APDE3ALMNASMN1; SMN2 | |
| SCHEMBL14300696 | 0.76 | ALDH1A1 (0.59) | KDM4ES1PR1LMNASMN1; SMN2ALDH1A1 | |
| SCHEMBL14300697 | 0.76 | ALDH1A1 (0.59) | KDM4ES1PR1LMNASMN1; SMN2ALDH1A1 | |
| SCHEMBL1410592 | 0.76 | RXRA (0.48) | RXRARXRBRXRGKDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110251187-A1 | HETEROCYCLIC COMPOUND | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2011-10-13 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110251187-A1 | HETEROCYCLIC COMPOUND | NES, BMI1, DOT1L | RXRA 1004/4885RXRB 1230/4885RXRG 1250/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.