Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 8/20 | 0.42 |
| ▸ | RAB9A | P51151 | 8/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 3/20 | 0.41 |
| ▸ | TSHR | P16473 | 4/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | MAOB | P27338 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1107837 | 0.89 | GAA (0.48) | NPC1RAB9ASMN1; SMN2TP53GAA | |
| SCHEMBL1107808 | 0.89 | NPC1 (0.42) | NPC1RAB9ASMN1; SMN2TP53GAA | |
| SCHEMBL1107835 | 0.79 | RAB9A (0.46) | NPC1RAB9ASMN1; SMN2GAATSHR | |
| SCHEMBL12313125 | 0.79 | NPC1 (0.42) | NPC1RAB9ASMN1; SMN2TP53GAA | |
| SCHEMBL1107850 | 0.79 | L3MBTL1 (0.41) | NPC1RAB9ASMN1; SMN2TP53GAA | |
| SCHEMBL1107819 | 0.78 | NPC1 (0.44) | NPC1RAB9ASMN1; SMN2TP53GAA | |
| SCHEMBL1107807 | 0.76 | NPC1 (0.42) | NPC1RAB9ASMN1; SMN2TP53KDM4E | |
| SCHEMBL1107871 | 0.76 | NPC1 (0.42) | NPC1RAB9ASMN1; SMN2TP53GAA | |
| SCHEMBL14095776 | 0.75 | NPC1 (0.42) | NPC1RAB9ASMN1; SMN2GAATSHR | |
| SCHEMBL14095751 | 0.74 | ATM (0.43) | NPC1RAB9ASMN1; SMN2TP53GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008104503-A1 | PESTICIDAL ACTIVE MIXTURES COMPRISING AMINOTHIAZOLINE COMPOUNDS | BASF SE (DE) | 2008-09-04 | — | — | WO | disclosed |