Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PABPC1 | P11940 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 0.40 |
| ▸ | GAA | P10253 | 3/20 | 0.40 |
| ▸ | HTT | P42858 | 2/20 | 0.40 |
| ▸ | GRM5 | P41594 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 4/20 | 0.40 |
| ▸ | RAB9A | P51151 | 4/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.39 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL464163 | 0.85 | PABPC1 (0.52) | PABPC1MAPTLMNASMN1; SMN2HTT | |
| SCHEMBL1842772 | 0.81 | PABPC1 (0.49) | PABPC1MAPTLMNASMN1; SMN2GAA | |
| SCHEMBL3742351 | 0.77 | PABPC1 (0.56) | PABPC1MAPTLMNASMN1; SMN2HTT | |
| SCHEMBL14302378 | 0.73 | PSMB11 (0.42) | PABPC1MAPTLMNASMN1; SMN2GAA | |
| SCHEMBL14307779 | 0.73 | LONP1 (0.42) | PABPC1MAPTLMNASMN1; SMN2GAA | |
| SCHEMBL464169 | 0.73 | LONP1 (0.42) | PABPC1MAPTLMNASMN1; SMN2GAA | |
| SCHEMBL464314 | 0.71 | LONP1 (0.41) | PABPC1MAPTLMNASMN1; SMN2GAA | |
| SCHEMBL14011262 | 0.69 | PABPC1 (0.51) | PABPC1MAPTLMNASMN1; SMN2GAA | |
| SCHEMBL3748694 | 0.69 | RAB9A (0.51) | PABPC1MAPTSMN1; SMN2NPC1RAB9A | |
| SCHEMBL29132984 | 0.69 | GAA (0.55) | PABPC1MAPTSMN1; SMN2GAAHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1958956-A2 | Peptidomimetic protease inhibitors | Vertex Pharmaceuticals Incorporated (US) | 2008-08-20 | — | — | EP | disclosed |