Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 10/20 | 0.68 |
| ▸ | RAB9A | P51151 | 10/20 | 0.68 |
| ▸ | KDM4E | B2RXH2 | 9/20 | 0.63 |
| ▸ | SMN1; SMN2 | Q16637 | 9/20 | 0.63 |
| ▸ | HPGD | P15428 | 8/20 | 0.63 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.63 |
| ▸ | MAPT | P10636 | 5/20 | 0.63 |
| ▸ | MEN1 | O00255 | 2/20 | 0.63 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.63 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.63 |
| ▸ | HSD17B10 | Q99714 | 5/20 | 0.59 |
| ▸ | MMP2 | P08253 | 1/20 | 0.59 |
| ▸ | MMP9 | P14780 | 1/20 | 0.59 |
| ▸ | MMP8 | P22894 | 1/20 | 0.59 |
| ▸ | MMP13 | P45452 | 1/20 | 0.59 |
| ▸ | TP53 | P04637 | 3/20 | 0.58 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.58 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.58 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.58 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.58 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12408905 | 0.88 | NPC1 (0.84) | NPC1RAB9AKDM4ESMN1; SMN2HPGD | |
| SCHEMBL14668236 | 0.87 | RAB9A (0.76) | NPC1RAB9AKDM4ESMN1; SMN2HPGD | |
| SCHEMBL11551873 | 0.86 | NPC1 (0.81) | NPC1RAB9AKDM4ESMN1; SMN2HPGD | |
| SCHEMBL2244364 | 0.86 | RAB9A (0.67) | NPC1RAB9AKDM4ESMN1; SMN2HPGD | |
| SCHEMBL13533826 | 0.84 | GPR119 (0.54) | NPC1RAB9AKDM4ESMN1; SMN2HPGD | |
| SCHEMBL2592335 | 0.84 | GPR119 (0.51) | NPC1RAB9AKDM4ESMN1; SMN2HPGD | |
| SCHEMBL10045322 | 0.82 | NPC1 (0.74) | NPC1RAB9AKDM4ESMN1; SMN2HPGD | |
| SCHEMBL17585007 | 0.82 | RAB9A (0.78) | NPC1RAB9AKDM4ESMN1; SMN2HPGD | |
| SCHEMBL24786645 | 0.81 | NPC1 (0.79) | NPC1RAB9AKDM4ESMN1; SMN2HPGD | |
| SCHEMBL16005432 | 0.81 | NPC1 (0.64) | NPC1RAB9AKDM4ESMN1; SMN2HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0977088-B1 | Use of an electrophotographic photosensitive member for an electrophotographic apparatus equipped with a semiconductor laser having wavelengths from 380nm to 500nm, and electrophotographic apparatus | CANON KK (JP) | 2008-08-20 | — | — | EP | disclosed |