Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FABP5 | Q01469 | 3/20 | 0.43 |
| ▸ | FABP7 | O15540 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | CASP3 | P42574 | 3/20 | 0.36 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.35 |
| ▸ | CA1 | P00915 | 1/20 | 0.34 |
| ▸ | CA2 | P00918 | 1/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | CASP1 | P29466 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL525667 | 0.83 | FABP5 (0.51) | FABP5FABP7KMT2ACASP3EPHX2 | |
| SCHEMBL29397325 | 0.76 | KMT2A (0.48) | FABP5FABP7KMT2ACASP3EPHX2 | |
| SCHEMBL119579 | 0.76 | KMT2A (0.48) | FABP5FABP7KMT2ACASP3EPHX2 | |
| SCHEMBL29649593 | 0.76 | KMT2A (0.48) | FABP5FABP7KMT2ACASP3EPHX2 | |
| SCHEMBL4600771 | 0.76 | FABP5 (0.45) | FABP5FABP7KMT2ACASP3EPHX2 | |
| Water SCHEMBL21056515 | 0.75 | KMT2A (0.47) | FABP5FABP7KMT2ACASP3EPHX2 | |
| SCHEMBL17699252 | 0.75 | FABP5 (0.50) | FABP5FABP7KMT2ACASP3EPHX2 | |
| SCHEMBL525363 | 0.74 | FABP5 (0.49) | FABP5FABP7KMT2ACASP3EPHX2 | |
| SCHEMBL524690 | 0.73 | FABP5 (0.48) | FABP5FABP7KMT2ACASP3EPHX2 | |
| SCHEMBL31317420 | 0.72 | KMT2A (0.44) | FABP5FABP7KMT2ACASP3EPHX2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2293847-B1 | DEPSIPEPTIDES AND THEIR THERAPEUTIC USE | KARUS THERAPEUTICS LTD (GB) | 2015-03-25 | — | — | EP | disclosed |
| EP-2293847-A1 | DEPSIPEPTIDES AND THEIR THERAPEUTIC USE | Karus Therapeutics Limited (GB) | 2011-03-16 | — | — | EP | disclosed |
| WO-2009141659-A1 | DEPSIPEPTIDES AND THEIR THERAPEUTIC USE | KARUS THERAPEUTICS LIMITED (GB) | 2009-11-26 | — | — | WO | disclosed |