Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADH1A | P07327 | 4/20 | 0.47 |
| ▸ | ADH1C | P00326 | 3/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13153399 | 0.82 | ADH1A (0.43) | ADH1AADH1CCYP1A2 | |
| SCHEMBL22693496 | 0.81 | ADH1A (0.33) | ADH1AADH1CCYP1A2SIGMAR1 | |
| SCHEMBL24621767 | 0.81 | ADH1A (0.33) | ADH1AADH1CCYP1A2SIGMAR1 | |
| SCHEMBL24435399 | 0.81 | ADH1A (0.33) | ADH1AADH1CCYP1A2SIGMAR1 | |
| SCHEMBL14446124 | 0.81 | ADH1A (0.33) | ADH1AADH1CSIGMAR1 | |
| SCHEMBL20747809 | 0.79 | ADH1A (0.40) | ADH1AADH1CCYP1A2 | |
| SCHEMBL26205899 | 0.78 | CYP1A2 (0.34) | ADH1AADH1CCYP1A2 | |
| SCHEMBL15932267 | 0.78 | SIGMAR1 (0.39) | ADH1ASIGMAR1 | |
| SCHEMBL27420202 | 0.78 | SIGMAR1 (0.32) | ADH1ACYP1A2SIGMAR1 | |
| SCHEMBL27420207 | 0.78 | SIGMAR1 (0.32) | ADH1ACYP1A2SIGMAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7414067-B2 | Ophthalmic compositions for treating ocular hypertension | MERCK & CO. INC. (US) | 2008-08-19 | — | — | US | disclosed |