Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | TLR4 | O00206 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL685482 | 0.78 | TSHR (0.38) | MAPTTLR4 | |
| SCHEMBL2388827 | 0.78 | TSHR (0.38) | MAPTTLR4 | |
| SCHEMBL10008216 | 0.78 | TSHR (0.38) | MAPTTLR4 | |
| SCHEMBL720591 | 0.78 | TSHR (0.38) | MAPTTLR4 | |
| SCHEMBL16077505 | 0.65 | CES2 (0.42) | ALDH1A1 | |
| SCHEMBL5270933 | 0.61 | ESR2 (0.41) | MAPTMEN1ALDH1A1LMNAKMT2A | |
| SCHEMBL10077330 | 0.59 | — | — | |
| SCHEMBL1719695 | 0.58 | TSHR (0.43) | — | |
| Beta-Pinene SCHEMBL900792 | 0.57 | TSHR (0.38) | — | |
| Beta-Pinene SCHEMBL1636093 | 0.57 | TSHR (0.38) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1193243-B1 | NOVEL PROCESS FOR PRODUCING BICYCLIC AMINO ALCOHOL | SHIONOGI & CO (JP) | 2008-08-13 | — | — | EP | disclosed |