Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR2 | Q92731 | 2/20 | 0.41 |
| ▸ | ESR1 | P03372 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13421816 | 0.72 | ESR2 (0.32) | ESR2ESR1 | |
| SCHEMBL8183244 | 0.72 | ESR2 (0.32) | ESR2ESR1 | |
| SCHEMBL3224313 | 0.67 | CA1 (0.32) | ESR2KMT2A | |
| SCHEMBL15957272 | 0.67 | CA1 (0.32) | ESR2KMT2A | |
| SCHEMBL6055844 | 0.66 | ESR2 (0.31) | ESR2ESR1MEN1ALDH1A1LMNA | |
| SCHEMBL13255133 | 0.64 | — | — | |
| SCHEMBL1266170 | 0.64 | — | — | |
| SCHEMBL19807604 | 0.64 | — | — | |
| SCHEMBL6435036 | 0.64 | AKR1B10 (0.33) | CYP3A4MEN1ALDH1A1LMNAMAPT | |
| SCHEMBL10008216 | 0.64 | TSHR (0.38) | ESR2ESR1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10435344-B2 | Reaction sequence for the synthesis of nootkatone, dihydronootkatone, and tetrahydronootkatone | BOARD OF SUPERVISORS OF LOUISIANA STATE UNIVERSITY AND AGRICULTURAL AND MECHANICAL COLLEGE (US) | 2019-10-08 | — | — | US | disclosed |
| US-20180362431-A1 | REACTION SEQUENCE FOR THE SYNTHESIS OF NOOTKATONE, DIHYDRONOOTKATONE, AND TETRAHYDRONOOTKATONE | BOARD OF SUPERVISORS OF LOUISIANA STATE UNIVERSITY AND AGRICULTURAL AND MECHANICAL COLLEGE (US) | 2018-12-20 | — | — | US | disclosed |
| WO-2017100437-A1 | REACTION SEQUENCE FOR THE SYNTHESIS OF NOOTKATONE, DIHYDRONOOTKATONE, AND TETRAHYDRONOOTKATONE | BOARD OF SUPERVISORS OF LOUISIANA STATE UNIVERSITY AND AGRICULTURAL AND MECHANICAL COLLEGE (US) | 2017-06-15 | — | — | WO | disclosed |
| EP-1868979-A1 | EFFICIENT AND ECONOMIC ASYMMETRIC SYNTHESIS OF NOOTKATONE, TETRAHYDRONOOTKATONE, THEIR PRECURSORS AND DERIVATIVES | Board of Supervisors of Louisiana State University and Agricultural and Mechanical College (US) | 2007-12-26 | — | — | EP | disclosed |
| WO-2006113285-A1 | EFFICIENT AND ECONOMIC ASYMMETRIC SYNTHESIS OF NOOTKATONE, TETRAHYDRONOOTKATONE, THEIR PRECURSORS AND DERIVATIVES | BOARD OF SUPERVISORS OF LOUISIANA STATE UNIVERSITY AND AGRICULTURAL AND MECHANICAL COLLEGE (US) | 2006-10-26 | — | — | WO | disclosed |
| US-20060235247-A1 | EFFICIENT AND ECONOMIC ASYMMETRIC SYNTHESIS OF NOOTKATONE, TETRAHYDRONOOTKATONE, THEIR PRECURSORS AND DERIVATIVES | BOARD OF SUPERVISORS OF LOUISIANA STATE UNIVERSITY AND AGRICULTURAL AND MECHANICAL COLLEGE | 2006-10-19 | — | — | US | disclosed |
| US-7112700-B1 | Efficient and economic asymmetric synthesis of nootkatone, tetrahydronootkatone, their precursors and derivatives | BOARD OF SUPERVISORS OF LOUISIANA STATE UNIVERSITY AND AGRICULTURAL AND MECHANICAL COLLEGE (US) | 2006-09-26 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180362431-A1 | REACTION SEQUENCE FOR THE SYNTHESIS OF NOOTKATONE, DIHYDRONOOTKATONE, AND TETRAHYDRONOOTKATONE | DHPS, DEGS1, CYP51A1 | ESR2 709/4885ESR1 1031/4885CYP3A4 126/4885 |
| US-20060235247-A1 | EFFICIENT AND ECONOMIC ASYMMETRIC SYNTHESIS OF NOOTKATONE, TETRAHYDRONOOTKATONE, THEIR PRECURSORS AND DERIVATIVES | COASY, CYP51A1, ADRB2 | ESR2 553/4885ESR1 1321/4885CYP3A4 174/4885 |
| US-10435344-B2 | Reaction sequence for the synthesis of nootkatone, dihydronootkatone, and tetrahydronootkatone | DHPS, DEGS1, CYP51A1 | ESR2 709/4885ESR1 1031/4885CYP3A4 126/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.