SCHEMBL14099672

SCHEMBL14099672

c1ccc(-c2ccc(N(c3ccccc3)c3ccc4c(-c5ccc6cc(-c7ccccc7)ccc6c5)c5cc(N(c6ccccc6)c6ccc(-c7ccccc7)cc6)ccc5c(-c5ccc6ccccc6c5)c4c3)cc2)cc1

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ESR1 P03372 4/20 0.41
ESR2 Q92731 4/20 0.41
HSD17B1 P14061 3/20 0.39
HSD17B2 P37059 3/20 0.39
ACMSD Q8TDX5 1/20 0.38
CYP17A1 P05093 1/20 0.37
CYP19A1 P11511 1/20 0.37
CYP11B1 P15538 1/20 0.37
CYP11B2 P19099 1/20 0.37
ALOX5 P09917 2/20 0.37
BACE1 P56817 1/20 0.36
CA1 P00915 1/20 0.36
CA2 P00918 1/20 0.36
CA9 Q16790 1/20 0.36
GPR84 Q9NQS5 1/20 0.36
CYP1A1 P04798 1/20 0.36
CYP1B1 Q16678 1/20 0.36
CYP1A2 P05177 3/20 0.35
CYP3A4 P08684 2/20 0.35
CYP2D6 P10635 2/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20130972 0.99 ESR1 (0.41) ESR1ESR2HSD17B1HSD17B2ACMSD
SCHEMBL15762788 0.98 ESR1 (0.42) ESR1ESR2HSD17B1HSD17B2ACMSD
SCHEMBL761413 0.98 ESR1 (0.39) ESR1ESR2HSD17B1HSD17B2ACMSD
SCHEMBL15762773 0.98 ESR1 (0.39) ESR1ESR2HSD17B1HSD17B2ACMSD
SCHEMBL14099685 0.97 ESR1 (0.39) ESR1ESR2HSD17B1HSD17B2ACMSD
SCHEMBL12337349 0.97 ESR1 (0.39) ESR1ESR2HSD17B1HSD17B2ACMSD
SCHEMBL19621666 0.97 ESR1 (0.39) ESR1ESR2HSD17B1HSD17B2ACMSD
SCHEMBL12014679 0.97 ESR1 (0.40) ESR1ESR2HSD17B1HSD17B2ACMSD
SCHEMBL14100085 0.96 ESR1 (0.40) ESR1ESR2HSD17B1HSD17B2ACMSD
SCHEMBL14099825 0.96 HSD17B1 (0.40) ESR1ESR2HSD17B1HSD17B2ACMSD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9620721-B2 OLEDs having high efficiency and excellent lifetime GLOBAL OLED TECHNOLOGY LLC (US) 2017-04-11 US disclosed
US-9620721-B2 OLEDs having high efficiency and excellent lifetime GLOBAL OLED TECHNOLOGY LLC (US) 2017-04-11 US disclosed
US-8795855-B2 OLEDs having high efficiency and excellent lifetime GLOBAL OLED TECHNOLOGY LLC (US) 2014-08-05 US disclosed
US-8795855-B2 OLEDs having high efficiency and excellent lifetime GLOBAL OLED TECHNOLOGY LLC (US) 2014-08-05 US disclosed
US-20140151676-A1 OLEDS HAVING HIGH EFFICIENCY AND EXCELLENT LIFETIME GLOBAL OLED TECHNOLOGY LLC (US) 2014-06-05 US disclosed
US-20140151676-A1 OLEDS HAVING HIGH EFFICIENCY AND EXCELLENT LIFETIME GLOBAL OLED TECHNOLOGY LLC (US) 2014-06-05 US disclosed
US-20080182129-A1 OLEDS HAVING HIGH EFFICIENCY AND EXCELLENT LIFETIME GLOBAL OLED TECHNOLOGY LLC 2008-07-31 US disclosed
US-20080182129-A1 OLEDS HAVING HIGH EFFICIENCY AND EXCELLENT LIFETIME GLOBAL OLED TECHNOLOGY LLC 2008-07-31 US disclosed