Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 7/20 | 0.41 |
| ▸ | ESR2 | Q92731 | 7/20 | 0.41 |
| ▸ | HSD17B1 | P14061 | 2/20 | 0.38 |
| ▸ | HSD17B2 | P37059 | 2/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | CYP2B6 | P20813 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | ACMSD | Q8TDX5 | 1/20 | 0.37 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.36 |
| ▸ | PTGES | O14684 | 1/20 | 0.36 |
| ▸ | CYP17A1 | P05093 | 1/20 | 0.36 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.36 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.36 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.36 |
| ▸ | BACE1 | P56817 | 1/20 | 0.36 |
| ▸ | CA1 | P00915 | 1/20 | 0.36 |
| ▸ | CA2 | P00918 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14099672 | 0.99 | ESR1 (0.41) | ESR1ESR2HSD17B1HSD17B2CYP1A2 | |
| SCHEMBL12337349 | 0.99 | ESR1 (0.39) | ESR1ESR2HSD17B1HSD17B2CYP1A2 | |
| SCHEMBL14099685 | 0.99 | ESR1 (0.39) | ESR1ESR2HSD17B1HSD17B2CYP1A2 | |
| SCHEMBL19621666 | 0.99 | ESR1 (0.39) | ESR1ESR2HSD17B1HSD17B2CYP1A2 | |
| SCHEMBL14100085 | 0.97 | ESR1 (0.40) | ESR1ESR2HSD17B1HSD17B2CYP1A2 | |
| SCHEMBL13333560 | 0.97 | ESR1 (0.40) | ESR1ESR2HSD17B1HSD17B2CYP1A2 | |
| SCHEMBL13333898 | 0.97 | ESR1 (0.38) | ESR1ESR2HSD17B1HSD17B2CYP1A2 | |
| SCHEMBL13333738 | 0.97 | ESR1 (0.40) | ESR1ESR2HSD17B1HSD17B2CYP1A2 | |
| SCHEMBL12928333 | 0.97 | ESR1 (0.37) | ESR1ESR2HSD17B1HSD17B2CYP1A2 | |
| SCHEMBL15762773 | 0.97 | ESR1 (0.39) | ESR1ESR2HSD17B1HSD17B2CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20190319197-A1 | ORGANIC COMPOUND, APPLICATIONS THEREOF, ORGANIC MIXTURE, AND ORGANIC ELECTRONIC DEVICE | GUANGZHOU CHINARAY OPTOELECTRONIC MATERIALS LTD. (CN) | 2019-10-17 | — | — | US | disclosed |
| US-20180130955-A1 | ORGANIC COMPOUND, MIXTURE COMPRISING SAME, COMPOSITE, AND ORGANIC ELECTRONIC COMPONENT | GUANGZHOU CHINARAY OPTOELECTRONICS MATERIALS LTD. (CN) | 2018-05-10 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180130955-A1 | ORGANIC COMPOUND, MIXTURE COMPRISING SAME, COMPOSITE, AND ORGANIC ELECTRONIC COMPONENT | OCIAD1, OCIAD2, SRD5A1 | ESR1 48/4885ESR2 58/4885HSD17B1 1220/4885 |
| US-20190319197-A1 | ORGANIC COMPOUND, APPLICATIONS THEREOF, ORGANIC MIXTURE, AND ORGANIC ELECTRONIC DEVICE | PIEZO1, OR10J3, OR51E2 | ESR1 33/4885ESR2 153/4885HSD17B1 629/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.